Relative biological effectiveness and microdosimetry of a mixed energy field of protons up to 200 MeV

J. B. Robertson; J. M. Eaddy; J. O. Archambeau; G. B. Coutrakon; D. W. Miller; M. F. Moyers; J. V. Siebers; J. M. Slater; J. F. Dicello

doi:10.1016/0273-1177(94)90477-4

Relative biological effectiveness and microdosimetry of a mixed energy field of protons up to 200 MeV

J. B. Robertson, J. M. Eaddy, J. O. Archambeau, G. B. Coutrakon, D. W. Miller, M. F. Moyers, J. V. Siebers, J. M. Slater, J. F. Dicello

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23 Scopus citations

Abstract

We have studied radiation effects utilizing the new 250 MeV Synchrotron at Loma Linda University Medical Center. In this paper we present the data collected for the survival of Chinese hamster lung (V79) cells, that were irradiated with a beam of mixed energy protons up to 200 MeV. The RBE for protons, when compared to ⁶⁰Co gamma rays, ranged from a low of 1.2 at the high energy portion of the field to 1.3+ at the low energy portion of the field. These results are consistent with the measured lineal energy (microdosimetric) spectra.

Original language	English (US)
Pages (from-to)	271-275
Number of pages	5
Journal	Advances in Space Research
Volume	14
Issue number	10
DOIs	https://doi.org/10.1016/0273-1177(94)90477-4
State	Published - Oct 1994
Externally published	Yes

ASJC Scopus subject areas

Aerospace Engineering
Astronomy and Astrophysics
Geophysics
Atmospheric Science
Space and Planetary Science
General Earth and Planetary Sciences

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title = "Relative biological effectiveness and microdosimetry of a mixed energy field of protons up to 200 MeV",

abstract = "We have studied radiation effects utilizing the new 250 MeV Synchrotron at Loma Linda University Medical Center. In this paper we present the data collected for the survival of Chinese hamster lung (V79) cells, that were irradiated with a beam of mixed energy protons up to 200 MeV. The RBE for protons, when compared to 60Co gamma rays, ranged from a low of 1.2 at the high energy portion of the field to 1.3+ at the low energy portion of the field. These results are consistent with the measured lineal energy (microdosimetric) spectra.",

author = "Robertson, {J. B.} and Eaddy, {J. M.} and Archambeau, {J. O.} and Coutrakon, {G. B.} and Miller, {D. W.} and Moyers, {M. F.} and Siebers, {J. V.} and Slater, {J. M.} and Dicello, {J. F.}",

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doi = "10.1016/0273-1177(94)90477-4",

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T1 - Relative biological effectiveness and microdosimetry of a mixed energy field of protons up to 200 MeV

AU - Robertson, J. B.

AU - Eaddy, J. M.

AU - Archambeau, J. O.

AU - Coutrakon, G. B.

AU - Miller, D. W.

AU - Moyers, M. F.

AU - Siebers, J. V.

AU - Slater, J. M.

AU - Dicello, J. F.

PY - 1994/10

Y1 - 1994/10

N2 - We have studied radiation effects utilizing the new 250 MeV Synchrotron at Loma Linda University Medical Center. In this paper we present the data collected for the survival of Chinese hamster lung (V79) cells, that were irradiated with a beam of mixed energy protons up to 200 MeV. The RBE for protons, when compared to 60Co gamma rays, ranged from a low of 1.2 at the high energy portion of the field to 1.3+ at the low energy portion of the field. These results are consistent with the measured lineal energy (microdosimetric) spectra.

AB - We have studied radiation effects utilizing the new 250 MeV Synchrotron at Loma Linda University Medical Center. In this paper we present the data collected for the survival of Chinese hamster lung (V79) cells, that were irradiated with a beam of mixed energy protons up to 200 MeV. The RBE for protons, when compared to 60Co gamma rays, ranged from a low of 1.2 at the high energy portion of the field to 1.3+ at the low energy portion of the field. These results are consistent with the measured lineal energy (microdosimetric) spectra.

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Relative biological effectiveness and microdosimetry of a mixed energy field of protons up to 200 MeV

Abstract

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