Relationship of Thoracic Aortic Calcium to Coronary Calcium and Its Progression (from the Multi-Ethnic Study of Atherosclerosis [MESA])

Juan J. Rivera, Khurram Nasir, Ronit Katz, Junichiro Takasu, Matthew Allison, Nathan D. Wong, R. Graham Barr, Jeffrey J. Carr, Roger S Blumenthal, Matthew J. Budoff

Research output: Contribution to journalArticle

Abstract

Thoracic aortic calcium (TAC) has been associated with a higher prevalence of coronary arterial calcium (CAC). The purpose of this study was to assess the relations between TAC and incident CAC and CAC progression in a cohort from the Multi-Ethnic Study of Atherosclerosis (MESA). MESA is a prospective cohort study of 6,814 participants free of clinical cardiovascular disease at entry who underwent noncontrast cardiac computed tomographic scanning at baseline examination and at a 2-year follow-up assessment. The independent associations between TAC and incident CAC in those without CAC at baseline and between TAC and CAC progression in those with CAC at baseline were investigated. The final study population consisted of 5,755 subjects (84%; mean age 62 ± 10 years, 48% men) who had follow-up CAC scores an average of 2.4 years later. Incident CAC was significantly higher in those with TAC compared with those without TAC at baseline (11 per 100 patient-years vs 6 per 100 patient-years). Similarly, TAC was associated with a higher CAC change (p

Original languageEnglish (US)
Pages (from-to)1562-1567
Number of pages6
JournalThe American Journal of Cardiology
Volume103
Issue number11
DOIs
StatePublished - Jun 1 2009

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Atherosclerosis
Thorax
Calcium
Cohort Studies
Cardiovascular Diseases
Prospective Studies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Relationship of Thoracic Aortic Calcium to Coronary Calcium and Its Progression (from the Multi-Ethnic Study of Atherosclerosis [MESA]). / Rivera, Juan J.; Nasir, Khurram; Katz, Ronit; Takasu, Junichiro; Allison, Matthew; Wong, Nathan D.; Barr, R. Graham; Carr, Jeffrey J.; Blumenthal, Roger S; Budoff, Matthew J.

In: The American Journal of Cardiology, Vol. 103, No. 11, 01.06.2009, p. 1562-1567.

Research output: Contribution to journalArticle

Rivera, Juan J. ; Nasir, Khurram ; Katz, Ronit ; Takasu, Junichiro ; Allison, Matthew ; Wong, Nathan D. ; Barr, R. Graham ; Carr, Jeffrey J. ; Blumenthal, Roger S ; Budoff, Matthew J. / Relationship of Thoracic Aortic Calcium to Coronary Calcium and Its Progression (from the Multi-Ethnic Study of Atherosclerosis [MESA]). In: The American Journal of Cardiology. 2009 ; Vol. 103, No. 11. pp. 1562-1567.
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