Relationship of serum and dietary magnesium to incident hypertension: The Atherosclerosis Risk in Communities (ARIC) Study

James M. Peacock, Aaron R. Folsom, Donna K. Arnett, John H. Eckfeldt, Moyses Szklo

Research output: Contribution to journalArticle

Abstract

PURPOSE: To examine the relationship of serum and dietary magnesium (Mg) with incident hypertension. The setting was the Atherosclerosis Risk in Communities (ARIC) Study, which included a biracial cohort, aged 45-64 years, from four U.S. communities. METHODS: This analysis included 7731 participants (4190 women and 3541 men) free of hypertension at baseline and followed six years. Fasting serum Mg was measured, and usual dietary intake was assessed with a food frequency questionnaire. RESULTS: After adjustment for age, race, and a number of other risk factors, the odds of incident hypertension across ascending quartiles of serum Mg were 1.0, 0.79, 0.85, and 0.70 in women (p trend = 0.01) and 1.0, 0.87, 0.87, and 0.82 in men (p trend = 0.16). We found no association between dietary Mg intake and incident hypertension. These associations were attenuated after the addition of baseline systolic blood pressure to the models. CONCLUSIONS: This study suggests that low Mg may play a modest role in the development of hypertension.

Original languageEnglish (US)
Pages (from-to)159-165
Number of pages7
JournalAnnals of Epidemiology
Volume9
Issue number3
DOIs
StatePublished - Apr 1999

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Magnesium
Atherosclerosis
Hypertension
Serum
Blood Pressure
Fasting
Food

Keywords

  • Blood Pressure
  • Epidemiology
  • Hypertension
  • Magnesium
  • Prospective Study

ASJC Scopus subject areas

  • Medicine(all)
  • Public Health, Environmental and Occupational Health
  • Epidemiology

Cite this

Relationship of serum and dietary magnesium to incident hypertension : The Atherosclerosis Risk in Communities (ARIC) Study. / Peacock, James M.; Folsom, Aaron R.; Arnett, Donna K.; Eckfeldt, John H.; Szklo, Moyses.

In: Annals of Epidemiology, Vol. 9, No. 3, 04.1999, p. 159-165.

Research output: Contribution to journalArticle

Peacock, James M. ; Folsom, Aaron R. ; Arnett, Donna K. ; Eckfeldt, John H. ; Szklo, Moyses. / Relationship of serum and dietary magnesium to incident hypertension : The Atherosclerosis Risk in Communities (ARIC) Study. In: Annals of Epidemiology. 1999 ; Vol. 9, No. 3. pp. 159-165.
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