The degree of nerve injury is difficult to determine and varies according to the mechanism of injury. Experimental nerve avulsion, cut, crush, and saw injuries were produced in male Sprague-Dawley rats. The extent of nerve damage was assessed histologically and by intraoperative observations on days 1, 8, and 21 post-injury. Nerve avulsions produced the most severe injury, followed by saw, crush, and cut mechanisms of injury. The intraoperative observations on day 1 were not predictors of the degree of injury at day 21. Avulsion injuries are most suitably treated secondarily by a nerve reconstruction technique, not by a primary repair.
ASJC Scopus subject areas