TY - JOUR
T1 - Relationship of dietary saturated fatty acids and body habitus to serum insulin concentrations
T2 - The normative aging study
AU - Parker, Donna R.
AU - Weiss, Scott T.
AU - Troisi, Rebecca
AU - Cassano, Patricia A.
AU - Vokonas, Pantel S.
AU - Landsberg, Lewis
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - The purpose of this study was to examine the relationship of body mass index, abdomen-hip ratio, and dietary intake 10 fasting and postprandial insulin concentrations among 652 men aged 43-85 y, followed in the Normative Aging Study. Log-transformed fasting insulin was significantly associated with body mass index, abdomen-hip ratio, total fat energy, and saturated fatty acid energy, with correlation coefficients ranging from 0.14 for total fat to 0.45 for body mass index. When multivariate models were used, body mass index, abdomen-hip ratio, and saturated fatty acid intake were statistically significant independent predictors of both fasting and postprandial insulin concentrations, after age, cigarette smoking, and physical activity were adjusted for. If saturated fatty acids as a percentage of total energy were to decrease from 14% to 8%, there would be an 18% decrease in fasting insulin and a 25% decrease in postprandial insulin. These data suggest that overall adiposity, abdominal obesity, and a diet high in saturated fatty acids are independent predictors for both fasting and postprandial insulin concentrations.
AB - The purpose of this study was to examine the relationship of body mass index, abdomen-hip ratio, and dietary intake 10 fasting and postprandial insulin concentrations among 652 men aged 43-85 y, followed in the Normative Aging Study. Log-transformed fasting insulin was significantly associated with body mass index, abdomen-hip ratio, total fat energy, and saturated fatty acid energy, with correlation coefficients ranging from 0.14 for total fat to 0.45 for body mass index. When multivariate models were used, body mass index, abdomen-hip ratio, and saturated fatty acid intake were statistically significant independent predictors of both fasting and postprandial insulin concentrations, after age, cigarette smoking, and physical activity were adjusted for. If saturated fatty acids as a percentage of total energy were to decrease from 14% to 8%, there would be an 18% decrease in fasting insulin and a 25% decrease in postprandial insulin. These data suggest that overall adiposity, abdominal obesity, and a diet high in saturated fatty acids are independent predictors for both fasting and postprandial insulin concentrations.
KW - Abdomen-hip ratio
KW - Hyperinsulinemia
KW - Saturated fatty acid
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U2 - 10.1093/ajcn/58.2.129
DO - 10.1093/ajcn/58.2.129
M3 - Article
C2 - 8338037
AN - SCOPUS:0027326602
SN - 0002-9165
VL - 58
SP - 129
EP - 136
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
IS - 2
ER -