TY - JOUR
T1 - Relationship of cognitive and functional impairment to depressive features in Alzheimer's disease and other dementias
AU - Payne, Jennifer L.
AU - Lyketsos, Constantine G.
AU - Steele, Cynthia
AU - Baker, Lori
AU - Galik, Elizabeth
AU - Kopunek, Susan
AU - Steinberg, Martin
AU - Warren, Andrew
PY - 1998
Y1 - 1998
N2 - Patients with clinical diagnoses of Alzheimer's disease, vascular dementia, or undifferentiated dementia were rated on standardized measures of depression, cognitive impairment, and functional impairment. Logistic regression was used to evaluate the relationship between functional or cognitive impairment, as well as their interaction, and depressive features in each group. This analysis revealed notable differences by type of dementia. The results imply that the mechanisms underlying depression in Alzheimer's disease may be different from those in vascular and other types of dementia. These results also provide indicators to the clinician for further evaluation of depression in different dementia subtypes.
AB - Patients with clinical diagnoses of Alzheimer's disease, vascular dementia, or undifferentiated dementia were rated on standardized measures of depression, cognitive impairment, and functional impairment. Logistic regression was used to evaluate the relationship between functional or cognitive impairment, as well as their interaction, and depressive features in each group. This analysis revealed notable differences by type of dementia. The results imply that the mechanisms underlying depression in Alzheimer's disease may be different from those in vascular and other types of dementia. These results also provide indicators to the clinician for further evaluation of depression in different dementia subtypes.
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U2 - 10.1176/jnp.10.4.440
DO - 10.1176/jnp.10.4.440
M3 - Article
C2 - 9813790
AN - SCOPUS:0031731457
SN - 0895-0172
VL - 10
SP - 440
EP - 447
JO - Journal of Neuropsychiatry and Clinical Neurosciences
JF - Journal of Neuropsychiatry and Clinical Neurosciences
IS - 4
ER -