Relationship of carotid distensibility and thoracic aorta calcification

Multi-ethnic study of atherosclerosis

Michael Blaha, Matthew J. Budoff, Juan J. Rivera, Ronit Katz, Daniel H. O'Leary, Joseph F. Polak, Junichiro Takasu, Roger S Blumenthal, Khurram Nasir

Research output: Contribution to journalArticle

Abstract

Stiffening of the central elastic arteries is one of the earliest detectable manifestations of adverse change within the vessel wall. Although an association between carotid artery stiffness and adverse events has been demonstrated, little is known about the relationship between stiffness and atherosclerosis. Even less is known about the impact of age, sex, and race on this association. To elucidate this question, we used baseline data from the Multi-Ethnic Study of Atherosclerosis (2000-2002). Carotid artery distensibility coefficient was calculated after visualization of the instantaneous waveform of the common carotid diameter using a high-resolution B-mode ultrasound. Thoracic aorta calcification was identified using noncontrast cardiac computed tomography. We found a strong association between decreasing distensibility coefficient (increasing carotid stiffness) and increasing thoracic aorta calcification, as well as a graded increase in the thoracic aorta calcification score (P

Original languageEnglish (US)
Pages (from-to)1408-1415
Number of pages8
JournalHypertension
Volume54
Issue number6
DOIs
StatePublished - Dec 2009

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Thoracic Aorta
Atherosclerosis
Carotid Arteries
Arteries
Tomography

Keywords

  • Carotid compliance
  • Carotid stiffness
  • Coronary calcification
  • Subclinical atherosclerosis
  • Thoracic aorta calcification

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Relationship of carotid distensibility and thoracic aorta calcification : Multi-ethnic study of atherosclerosis. / Blaha, Michael; Budoff, Matthew J.; Rivera, Juan J.; Katz, Ronit; O'Leary, Daniel H.; Polak, Joseph F.; Takasu, Junichiro; Blumenthal, Roger S; Nasir, Khurram.

In: Hypertension, Vol. 54, No. 6, 12.2009, p. 1408-1415.

Research output: Contribution to journalArticle

Blaha, Michael ; Budoff, Matthew J. ; Rivera, Juan J. ; Katz, Ronit ; O'Leary, Daniel H. ; Polak, Joseph F. ; Takasu, Junichiro ; Blumenthal, Roger S ; Nasir, Khurram. / Relationship of carotid distensibility and thoracic aorta calcification : Multi-ethnic study of atherosclerosis. In: Hypertension. 2009 ; Vol. 54, No. 6. pp. 1408-1415.
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