Relationship between use of proton pump inhibitors and igf system in older subjects

Marcello Maggio; F. Lauretani; F. De Vita; V. Butto; C. Cattabiani; S. Masoni; E. Sutti; G. Bondi; E. Dall'Aglio; S. Bandinelli; A. Corsonello; A. M. Abbatecola; F. Lattanzio; L. Ferrucci; G. P. Ceda

doi:10.1007/s12603-013-0430-z

Relationship between use of proton pump inhibitors and igf system in older subjects

Marcello Maggio, F. Lauretani, F. De Vita, V. Butto, C. Cattabiani, S. Masoni, E. Sutti, G. Bondi, E. Dall'Aglio, S. Bandinelli, A. Corsonello, A. M. Abbatecola, F. Lattanzio, L. Ferrucci, G. P. Ceda

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Objectives: to investigate the effects of proton pump inhibitors (PPIs) on the insulin-like-growth factor 1(IGF-1) system in the elderly. Design: cross-sectional. Setting: InCHIANTI study. Participants: 938 older subjects (536 women, 402 men, mean age 75.7±7.4 years). Measurements: complete data on age, sex, BMI, liver function, medications, dietary intake, IGF-1, IGF-binding protein-1 and -3 (IGFBP-1, IGFBP-3). Results: Participants were categorized by PPI use, identifying 903 PPI non users and 35 users. After adjusting for age, male PPI users (107.0 ± 69.6 vs 127.1 ± 55.8, p

Original language	English (US)
Pages (from-to)	420-423
Number of pages	4
Journal	The journal of nutrition, health & aging
Volume	18
Issue number	4
DOIs	https://doi.org/10.1007/s12603-013-0430-z
State	Published - 2014
Externally published	Yes

Keywords

IGF-1
Older subjects
Proton pump inhibitors

ASJC Scopus subject areas

Medicine (miscellaneous)
Nutrition and Dietetics
Geriatrics and Gerontology
General Medicine

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Maggio, M., Lauretani, F., De Vita, F., Butto, V., Cattabiani, C., Masoni, S., Sutti, E., Bondi, G., Dall'Aglio, E., Bandinelli, S., Corsonello, A., Abbatecola, A. M., Lattanzio, F., Ferrucci, L., & Ceda, G. P. (2014). Relationship between use of proton pump inhibitors and igf system in older subjects. The journal of nutrition, health & aging, 18(4), 420-423. https://doi.org/10.1007/s12603-013-0430-z

Maggio, M, Lauretani, F, De Vita, F, Butto, V, Cattabiani, C, Masoni, S, Sutti, E, Bondi, G, Dall'Aglio, E, Bandinelli, S, Corsonello, A, Abbatecola, AM, Lattanzio, F, Ferrucci, L & Ceda, GP 2014, 'Relationship between use of proton pump inhibitors and igf system in older subjects', The journal of nutrition, health & aging, vol. 18, no. 4, pp. 420-423. https://doi.org/10.1007/s12603-013-0430-z

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abstract = "Objectives: to investigate the effects of proton pump inhibitors (PPIs) on the insulin-like-growth factor 1(IGF-1) system in the elderly. Design: cross-sectional. Setting: InCHIANTI study. Participants: 938 older subjects (536 women, 402 men, mean age 75.7±7.4 years). Measurements: complete data on age, sex, BMI, liver function, medications, dietary intake, IGF-1, IGF-binding protein-1 and -3 (IGFBP-1, IGFBP-3). Results: Participants were categorized by PPI use, identifying 903 PPI non users and 35 users. After adjusting for age, male PPI users (107.0 ± 69.6 vs 127.1 ± 55.8, p",

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doi = "10.1007/s12603-013-0430-z",

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AU - Maggio, Marcello

AU - Lauretani, F.

AU - De Vita, F.

AU - Butto, V.

AU - Cattabiani, C.

AU - Masoni, S.

AU - Sutti, E.

AU - Bondi, G.

AU - Dall'Aglio, E.

AU - Bandinelli, S.

AU - Corsonello, A.

AU - Abbatecola, A. M.

AU - Lattanzio, F.

AU - Ferrucci, L.

AU - Ceda, G. P.

PY - 2014

Y1 - 2014

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AB - Objectives: to investigate the effects of proton pump inhibitors (PPIs) on the insulin-like-growth factor 1(IGF-1) system in the elderly. Design: cross-sectional. Setting: InCHIANTI study. Participants: 938 older subjects (536 women, 402 men, mean age 75.7±7.4 years). Measurements: complete data on age, sex, BMI, liver function, medications, dietary intake, IGF-1, IGF-binding protein-1 and -3 (IGFBP-1, IGFBP-3). Results: Participants were categorized by PPI use, identifying 903 PPI non users and 35 users. After adjusting for age, male PPI users (107.0 ± 69.6 vs 127.1 ± 55.8, p

KW - IGF-1

KW - Older subjects

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Relationship between use of proton pump inhibitors and igf system in older subjects

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