Abstract
Purpose: Our aim was to investigate the proportion of individuals with depression and its association with diabetic retinopathy and visual impairment in a cohort with 25 or more years of type 1 diabetes. Methods: This was a cross-sectional analysis at the 25-year follow-up of the population-based cohort of the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Examinations followed standardized protocols and included clinical and ophthalmic evaluations and questionnaires to assess current and past medical history, use of medications, and cigarette smoking. The Center for Epidemiologic Studies Depression Scale (CES-D) was administered to all participants. Depression was defined as use of antidepressant or CES-D score ≥16. Results: A total of 484 individuals were included in the analysis. The proportion of depression was 37.8% (95% confidence interval 33.4-42.3%). A higher proportion of individuals with depression was observed among those with more severe diabetic retinopathy and visual impairment. However these associations were not statistically significant while controlling for other factors in the multivariable analyses. Conclusions: Diabetic retinopathy severity and visual acuity in persons with long duration of type 1 diabetes were not cross-sectionally associated with depression in this cohort.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 196-203 |
| Number of pages | 8 |
| Journal | Ophthalmic Epidemiology |
| Volume | 19 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2012 |
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Keywords
- Depression
- Diabetic retinopathy
- Epidemiology
- Type 1 diabetes
- Visual impairment
ASJC Scopus subject areas
- Ophthalmology
- Epidemiology
Cite this
Relationship between retinopathy severity, visual impairment and depression in persons with long-term type 1 diabetes. / Hirai, Flavio E.; Tielsch, James M.; Klein, Barbara E K; Klein, Ronald.
In: Ophthalmic Epidemiology, Vol. 19, No. 4, 08.2012, p. 196-203.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Relationship between retinopathy severity, visual impairment and depression in persons with long-term type 1 diabetes
AU - Hirai, Flavio E.
AU - Tielsch, James M.
AU - Klein, Barbara E K
AU - Klein, Ronald
PY - 2012/8
Y1 - 2012/8
N2 - Purpose: Our aim was to investigate the proportion of individuals with depression and its association with diabetic retinopathy and visual impairment in a cohort with 25 or more years of type 1 diabetes. Methods: This was a cross-sectional analysis at the 25-year follow-up of the population-based cohort of the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Examinations followed standardized protocols and included clinical and ophthalmic evaluations and questionnaires to assess current and past medical history, use of medications, and cigarette smoking. The Center for Epidemiologic Studies Depression Scale (CES-D) was administered to all participants. Depression was defined as use of antidepressant or CES-D score ≥16. Results: A total of 484 individuals were included in the analysis. The proportion of depression was 37.8% (95% confidence interval 33.4-42.3%). A higher proportion of individuals with depression was observed among those with more severe diabetic retinopathy and visual impairment. However these associations were not statistically significant while controlling for other factors in the multivariable analyses. Conclusions: Diabetic retinopathy severity and visual acuity in persons with long duration of type 1 diabetes were not cross-sectionally associated with depression in this cohort.
AB - Purpose: Our aim was to investigate the proportion of individuals with depression and its association with diabetic retinopathy and visual impairment in a cohort with 25 or more years of type 1 diabetes. Methods: This was a cross-sectional analysis at the 25-year follow-up of the population-based cohort of the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Examinations followed standardized protocols and included clinical and ophthalmic evaluations and questionnaires to assess current and past medical history, use of medications, and cigarette smoking. The Center for Epidemiologic Studies Depression Scale (CES-D) was administered to all participants. Depression was defined as use of antidepressant or CES-D score ≥16. Results: A total of 484 individuals were included in the analysis. The proportion of depression was 37.8% (95% confidence interval 33.4-42.3%). A higher proportion of individuals with depression was observed among those with more severe diabetic retinopathy and visual impairment. However these associations were not statistically significant while controlling for other factors in the multivariable analyses. Conclusions: Diabetic retinopathy severity and visual acuity in persons with long duration of type 1 diabetes were not cross-sectionally associated with depression in this cohort.
KW - Depression
KW - Diabetic retinopathy
KW - Epidemiology
KW - Type 1 diabetes
KW - Visual impairment
UR - http://www.scopus.com/inward/record.url?scp=84863707342&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84863707342&partnerID=8YFLogxK
U2 - 10.3109/09286586.2012.692006
DO - 10.3109/09286586.2012.692006
M3 - Article
C2 - 22775274
AN - SCOPUS:84863707342
VL - 19
SP - 196
EP - 203
JO - Ophthalmic Epidemiology
JF - Ophthalmic Epidemiology
SN - 0928-6586
IS - 4
ER -