Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli

M. H. Merson, F. Orskov, I. Orskov, R. B. Sack, I. Huq, F. T. Koster

Research output: Contribution to journalArticle

Abstract

The authors examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic E. coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86%) belonged to the one of four O serogroups, and 56 (81%) of these strains belonged to one of six O:K:H serotypes. In contrast, 34 strains producing only heat-stable toxin were distributed among 15 O serogroups, and six strains producing only heat-labile toxin were distributed among six O serogroups. Twelve strains producing heat-labile and heat-stable toxins and five strains producing heat-stable toxin were found which had the same serotype (O78:K -:H12) and biotype. It appears that at least in one geographic setting E. coli strains producing both heat-labile and heat-stable toxins are more restricted in their O groups and O:K:H serotypes than E. coli that produce only heat-stable toxin and that certain serobiotypes may commonly include strains which produce both toxin types.

Original languageEnglish (US)
Pages (from-to)325-329
Number of pages5
JournalInfection and Immunity
Volume23
Issue number2
StatePublished - 1979
Externally publishedYes

Fingerprint

Enterotoxigenic Escherichia coli
Enterotoxins
Hot Temperature
Serogroup
Escherichia coli
Bangladesh
Cholera
Diarrhea

ASJC Scopus subject areas

  • Immunology

Cite this

Merson, M. H., Orskov, F., Orskov, I., Sack, R. B., Huq, I., & Koster, F. T. (1979). Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. Infection and Immunity, 23(2), 325-329.

Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. / Merson, M. H.; Orskov, F.; Orskov, I.; Sack, R. B.; Huq, I.; Koster, F. T.

In: Infection and Immunity, Vol. 23, No. 2, 1979, p. 325-329.

Research output: Contribution to journalArticle

Merson, MH, Orskov, F, Orskov, I, Sack, RB, Huq, I & Koster, FT 1979, 'Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli', Infection and Immunity, vol. 23, no. 2, pp. 325-329.
Merson MH, Orskov F, Orskov I, Sack RB, Huq I, Koster FT. Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. Infection and Immunity. 1979;23(2):325-329.
Merson, M. H. ; Orskov, F. ; Orskov, I. ; Sack, R. B. ; Huq, I. ; Koster, F. T. / Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. In: Infection and Immunity. 1979 ; Vol. 23, No. 2. pp. 325-329.
@article{a89328a7be69463a820912b18027bb36,
title = "Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli",
abstract = "The authors examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic E. coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86{\%}) belonged to the one of four O serogroups, and 56 (81{\%}) of these strains belonged to one of six O:K:H serotypes. In contrast, 34 strains producing only heat-stable toxin were distributed among 15 O serogroups, and six strains producing only heat-labile toxin were distributed among six O serogroups. Twelve strains producing heat-labile and heat-stable toxins and five strains producing heat-stable toxin were found which had the same serotype (O78:K -:H12) and biotype. It appears that at least in one geographic setting E. coli strains producing both heat-labile and heat-stable toxins are more restricted in their O groups and O:K:H serotypes than E. coli that produce only heat-stable toxin and that certain serobiotypes may commonly include strains which produce both toxin types.",
author = "Merson, {M. H.} and F. Orskov and I. Orskov and Sack, {R. B.} and I. Huq and Koster, {F. T.}",
year = "1979",
language = "English (US)",
volume = "23",
pages = "325--329",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "2",

}

TY - JOUR

T1 - Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli

AU - Merson, M. H.

AU - Orskov, F.

AU - Orskov, I.

AU - Sack, R. B.

AU - Huq, I.

AU - Koster, F. T.

PY - 1979

Y1 - 1979

N2 - The authors examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic E. coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86%) belonged to the one of four O serogroups, and 56 (81%) of these strains belonged to one of six O:K:H serotypes. In contrast, 34 strains producing only heat-stable toxin were distributed among 15 O serogroups, and six strains producing only heat-labile toxin were distributed among six O serogroups. Twelve strains producing heat-labile and heat-stable toxins and five strains producing heat-stable toxin were found which had the same serotype (O78:K -:H12) and biotype. It appears that at least in one geographic setting E. coli strains producing both heat-labile and heat-stable toxins are more restricted in their O groups and O:K:H serotypes than E. coli that produce only heat-stable toxin and that certain serobiotypes may commonly include strains which produce both toxin types.

AB - The authors examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic E. coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86%) belonged to the one of four O serogroups, and 56 (81%) of these strains belonged to one of six O:K:H serotypes. In contrast, 34 strains producing only heat-stable toxin were distributed among 15 O serogroups, and six strains producing only heat-labile toxin were distributed among six O serogroups. Twelve strains producing heat-labile and heat-stable toxins and five strains producing heat-stable toxin were found which had the same serotype (O78:K -:H12) and biotype. It appears that at least in one geographic setting E. coli strains producing both heat-labile and heat-stable toxins are more restricted in their O groups and O:K:H serotypes than E. coli that produce only heat-stable toxin and that certain serobiotypes may commonly include strains which produce both toxin types.

UR - http://www.scopus.com/inward/record.url?scp=0018347416&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018347416&partnerID=8YFLogxK

M3 - Article

C2 - 370013

AN - SCOPUS:0018347416

VL - 23

SP - 325

EP - 329

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 2

ER -