Relationship between cigarette use and mood/anxiety disorders among pregnant methadone-maintained patients

Margaret S. Chisolm, Michelle Tuten, Emily C. Brigham, Eric C. Strain, Hendre E. Jones

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


This study investigates the association between cigarette use and current mood/anxiety disorders among pregnant opioid-dependent patients. Pregnant methadone-maintained women (N = 122) completed the Addiction Severity Index and Structured Clinical Interview for DSM-IV. Participants were categorized based on past 30 days cigarette use: no (n = 15) and any smoking (n = 107); this latter group was then subdivided into light (one to ten cigarettes/day; n = 55), and heavy smokers (11 cigarettes/day; n = 52). Any smoking was significantly associated with any current mood/anxiety disorder (p < 0.001), any current mood disorder (p = 0.007), and any current anxiety disorder (p < 0.001). No significant association was found between specific level of cigarette use and mood/anxiety disorders. This association between smoking and psychiatric disorders has implications for the mental and physical health of methadone-maintained women and their children, and may contribute to the understanding of the physiological mechanisms underlying smoking and nicotine dependence.

Original languageEnglish (US)
Pages (from-to)422-429
Number of pages8
JournalAmerican Journal on Addictions
Issue number5
StatePublished - Aug 10 2009

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Clinical Psychology
  • Psychiatry and Mental health


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