Relationship between chronic fatigue syndrome and neurally mediated hypotension

Research output: Contribution to journalReview articlepeer-review


Chronic fatigue syndrome is a chronic debilitating disease that afflicts 4/1000 of the general population. The pathophysiologic basis for this condition is unknown, and no known consistently effective therapy has been identified. Recent studies have reported a link between the chronic fatigue syndrome and neurally mediated hypotension, a common abnormality of blood pressure regulation. In nonrandomized studies, treatment directed at neurally mediated hypotension has been effective in treating the symptoms of the chronic fatigue syndrome in two-thirds of patients. Prospective randomized trials are now in progress.

Original languageEnglish (US)
Pages (from-to)125-134
Number of pages10
JournalCardiology in Review
Issue number3
StatePublished - Jan 1 1998


  • Chronic fatigue syndrome
  • Fatigue
  • Neurally mediated hypotension
  • Vasodepressor syncope

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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