Relationship between bone cross-sectional area and indices of peripheral artery disease

Claudio Pedone; Simone Scarlata; Nicola Napoli; Fulvio Lauretani; Stefania Bandinelli; Luigi Ferrucci; Raffaele Antonelli Incalzi

doi:10.1007/s00223-013-9782-y

Relationship between bone cross-sectional area and indices of peripheral artery disease

Claudio Pedone, Simone Scarlata, Nicola Napoli, Fulvio Lauretani, Stefania Bandinelli, Luigi Ferrucci, Raffaele Antonelli Incalzi

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Most studies on the relationship between bone mineral density and atherosclerosis have used dual-energy X-ray absorptiometry, but this method is relatively insensitive to bone geometry. The aim of this study was to investigate the relationship between bone area and indices of carotid and peripheral atherosclerosis. We studied 841 persons aged 65 years or older (women = 444, mean age 73.8 years; men = 397, mean age = 75.3 years) enrolled in the InCHIANTI study and free from active malignancies, chronic use of bisphosphonates or steroids, and estrogen replacement therapy. The tibial cortical and total cross-sectional area (CSA) were measured by peripheral quantitative computed tomography and their ratio was calculated (cortical/total cross-sectional area ratio, cCSA/tCSA); carotid plaques were screened by echography, and peripheral artery disease (PAD) was defined as an ankle/brachial index

Original language	English (US)
Pages (from-to)	508-516
Number of pages	9
Journal	Calcified Tissue International
Volume	93
Issue number	6
DOIs	https://doi.org/10.1007/s00223-013-9782-y
State	Published - Dec 2013
Externally published	Yes

Keywords

Atherosclerosis
Bone cross-sectional area
Elderly
Osteoporosis
Peripheral artery disease
Women

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1007/s00223-013-9782-y

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title = "Relationship between bone cross-sectional area and indices of peripheral artery disease",

abstract = "Most studies on the relationship between bone mineral density and atherosclerosis have used dual-energy X-ray absorptiometry, but this method is relatively insensitive to bone geometry. The aim of this study was to investigate the relationship between bone area and indices of carotid and peripheral atherosclerosis. We studied 841 persons aged 65 years or older (women = 444, mean age 73.8 years; men = 397, mean age = 75.3 years) enrolled in the InCHIANTI study and free from active malignancies, chronic use of bisphosphonates or steroids, and estrogen replacement therapy. The tibial cortical and total cross-sectional area (CSA) were measured by peripheral quantitative computed tomography and their ratio was calculated (cortical/total cross-sectional area ratio, cCSA/tCSA); carotid plaques were screened by echography, and peripheral artery disease (PAD) was defined as an ankle/brachial index ",

keywords = "Atherosclerosis, Bone cross-sectional area, Elderly, Osteoporosis, Peripheral artery disease, Women",

author = "Claudio Pedone and Simone Scarlata and Nicola Napoli and Fulvio Lauretani and Stefania Bandinelli and Luigi Ferrucci and Incalzi, {Raffaele Antonelli}",

year = "2013",

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doi = "10.1007/s00223-013-9782-y",

language = "English (US)",

volume = "93",

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AU - Pedone, Claudio

AU - Scarlata, Simone

AU - Napoli, Nicola

AU - Lauretani, Fulvio

AU - Bandinelli, Stefania

AU - Ferrucci, Luigi

AU - Incalzi, Raffaele Antonelli

PY - 2013/12

Y1 - 2013/12

N2 - Most studies on the relationship between bone mineral density and atherosclerosis have used dual-energy X-ray absorptiometry, but this method is relatively insensitive to bone geometry. The aim of this study was to investigate the relationship between bone area and indices of carotid and peripheral atherosclerosis. We studied 841 persons aged 65 years or older (women = 444, mean age 73.8 years; men = 397, mean age = 75.3 years) enrolled in the InCHIANTI study and free from active malignancies, chronic use of bisphosphonates or steroids, and estrogen replacement therapy. The tibial cortical and total cross-sectional area (CSA) were measured by peripheral quantitative computed tomography and their ratio was calculated (cortical/total cross-sectional area ratio, cCSA/tCSA); carotid plaques were screened by echography, and peripheral artery disease (PAD) was defined as an ankle/brachial index

AB - Most studies on the relationship between bone mineral density and atherosclerosis have used dual-energy X-ray absorptiometry, but this method is relatively insensitive to bone geometry. The aim of this study was to investigate the relationship between bone area and indices of carotid and peripheral atherosclerosis. We studied 841 persons aged 65 years or older (women = 444, mean age 73.8 years; men = 397, mean age = 75.3 years) enrolled in the InCHIANTI study and free from active malignancies, chronic use of bisphosphonates or steroids, and estrogen replacement therapy. The tibial cortical and total cross-sectional area (CSA) were measured by peripheral quantitative computed tomography and their ratio was calculated (cortical/total cross-sectional area ratio, cCSA/tCSA); carotid plaques were screened by echography, and peripheral artery disease (PAD) was defined as an ankle/brachial index

KW - Atherosclerosis

KW - Bone cross-sectional area

KW - Elderly

KW - Osteoporosis

KW - Peripheral artery disease

KW - Women

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JO - Calcified Tissue International

JF - Calcified Tissue International

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ER -

Relationship between bone cross-sectional area and indices of peripheral artery disease

Abstract

Keywords

ASJC Scopus subject areas

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