Relationship Between Arrhythmogenic Right Ventricular Dysplasia and Exercise

Abhishek C. Sawant, Hugh Calkins

Research output: Contribution to journalArticle

Abstract

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is rare cardiomyopathy associated with life-threatening arrhythmias and increased risk of sudden cardiac death. In addition to mutations in desmosomal genes, environmental factors such as exercise have been implicated in the pathogenesis of the disease. Recent studies have shown that exercise may be associated with adverse outcomes in ARVD/C patients. Based on current evidence, ARVD/C patients are recommended to limit exercise irrespective of their mutation status. In addition, some studies have suggested the presence of an entirely acquired form of the disease caused by exercise that has been dubbed exercise-induced ARVD/C.

Original languageEnglish (US)
Pages (from-to)195-206
Number of pages12
JournalCardiac Electrophysiology Clinics
Volume7
Issue number2
DOIs
StatePublished - Jun 1 2015

    Fingerprint

Keywords

  • Arrhythmogenic right ventricular dysplasia/cardiomyopathy
  • Exercise
  • Exercise-induced cardiomyopathy
  • Sudden cardiac death

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Medicine(all)

Cite this