Relation of uric acid to serum levels of high-sensitivity c-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis

Tanya Keenan, Michael Blaha, Khurram Nasir, Michael G. Silverman, Rajesh Tota-Maharaj, Jose A M Carvalho, Raquel D. Conceição, Roger S Blumenthal, Raul D. Santos

Research output: Contribution to journalArticle

Abstract

Increased uric acid (UA) is strongly linked to cardiovascular disease. However, the independent role of UA is still debated because it is associated with several cardiovascular risk factors including obesity and metabolic syndrome. This study assessed the association of UA with increased high-sensitivity C-reactive protein (hs-CRP), increased ratio of triglyceride to high-density lipoprotein cholesterol (TG/HDL), sonographically detected hepatic steatosis, and their clustering in the presence and absence of obesity and metabolic syndrome. We evaluated 3,518 employed subjects without clinical cardiovascular disease from November 2008 through July 2010. Prevalence of hs-CRP

Original languageEnglish (US)
Pages (from-to)1787-1792
Number of pages6
JournalThe American Journal of Cardiology
Volume110
Issue number12
DOIs
StatePublished - Dec 15 2012

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Uric Acid
HDL Cholesterol
Triglycerides
C-Reactive Protein
Liver
Cardiovascular Diseases
Obesity
Serum
Proteins
Cluster Analysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Relation of uric acid to serum levels of high-sensitivity c-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis. / Keenan, Tanya; Blaha, Michael; Nasir, Khurram; Silverman, Michael G.; Tota-Maharaj, Rajesh; Carvalho, Jose A M; Conceição, Raquel D.; Blumenthal, Roger S; Santos, Raul D.

In: The American Journal of Cardiology, Vol. 110, No. 12, 15.12.2012, p. 1787-1792.

Research output: Contribution to journalArticle

Keenan, Tanya ; Blaha, Michael ; Nasir, Khurram ; Silverman, Michael G. ; Tota-Maharaj, Rajesh ; Carvalho, Jose A M ; Conceição, Raquel D. ; Blumenthal, Roger S ; Santos, Raul D. / Relation of uric acid to serum levels of high-sensitivity c-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis. In: The American Journal of Cardiology. 2012 ; Vol. 110, No. 12. pp. 1787-1792.
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