Hypertension can damage small blood vessels, and this effect is best seen in the arterioles of the kidney, which undergo fibrinoid necrosis. It also has a potentiating effect on arteriosclerosis of the larger vessels such as the coronary, carotid, and vertebral arteries. The relation of hypertension to endarteritis fibrosa of the interlobular arteries of the kidney is not clear; while at one time it was felt that hypertension caused this lesion, recently acquired information raises the possibility that the arterial changes result from intravascular coagulation and may cause or accelerate the hypertension.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine