Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation

Nicholas Shaffer, Bryn Martin, Brandon Rocque, Casey Madura, Bermans Iskandar, Oliver Wieben, Stephen Dombrowski, Mark Luciano, John Oshinski, Francis Loth

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study investigates the use of longitudinal impedance (LI) as a means to quantify the severity of Type I Chiari Malformation (CMI). LI was analyzed in image-based models of the cervical spinal subarachnoid space of 22 CMI patients and 10 healthy volunteers. LI was then compared with the cerebellar tonsil herniation (CTH) measured by two neurosurgeons. Results showed that both LI and CTH differentiated CMI patients from healthy volunteers, but lacked the specificity to differentiate symptomatic and asymptomatic patients.

Original languageEnglish (US)
Title of host publicationASME 2013 Summer Bioengineering Conference, SBC 2013
DOIs
StatePublished - Dec 1 2013
Externally publishedYes
EventASME 2013 Summer Bioengineering Conference, SBC 2013 - Sunriver, OR, United States
Duration: Jun 26 2013Jun 29 2013

Publication series

NameASME 2013 Summer Bioengineering Conference, SBC 2013
Volume1 B

Other

OtherASME 2013 Summer Bioengineering Conference, SBC 2013
CountryUnited States
CitySunriver, OR
Period6/26/136/29/13

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Mechanical Engineering

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