Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation

Nicholas Shaffer; Bryn Martin; Brandon Rocque; Casey Madura; Bermans Iskandar; Oliver Wieben; Stephen Dombrowski; Mark Luciano; John Oshinski; Francis Loth

doi:10.1115/SBC2013-14808

Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation

Nicholas Shaffer, Bryn Martin, Brandon Rocque, Casey Madura, Bermans Iskandar, Oliver Wieben, Stephen Dombrowski, Mark Luciano, John Oshinski, Francis Loth

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This study investigates the use of longitudinal impedance (LI) as a means to quantify the severity of Type I Chiari Malformation (CMI). LI was analyzed in image-based models of the cervical spinal subarachnoid space of 22 CMI patients and 10 healthy volunteers. LI was then compared with the cerebellar tonsil herniation (CTH) measured by two neurosurgeons. Results showed that both LI and CTH differentiated CMI patients from healthy volunteers, but lacked the specificity to differentiate symptomatic and asymptomatic patients.

Original language	English (US)
Title of host publication	ASME 2013 Summer Bioengineering Conference, SBC 2013
DOIs	https://doi.org/10.1115/SBC2013-14808
State	Published - 2013
Externally published	Yes
Event	ASME 2013 Summer Bioengineering Conference, SBC 2013 - Sunriver, OR, United States Duration: Jun 26 2013 → Jun 29 2013

Publication series

Name	ASME 2013 Summer Bioengineering Conference, SBC 2013
Volume	1 B

Other

Other	ASME 2013 Summer Bioengineering Conference, SBC 2013
Country/Territory	United States
City	Sunriver, OR
Period	6/26/13 → 6/29/13

ASJC Scopus subject areas

Bioengineering
Biotechnology
Mechanical Engineering

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10.1115/SBC2013-14808

Cite this

Shaffer, N., Martin, B., Rocque, B., Madura, C., Iskandar, B., Wieben, O., Dombrowski, S., Luciano, M., Oshinski, J., & Loth, F. (2013). Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation. In ASME 2013 Summer Bioengineering Conference, SBC 2013 (ASME 2013 Summer Bioengineering Conference, SBC 2013; Vol. 1 B). https://doi.org/10.1115/SBC2013-14808

Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation. / Shaffer, Nicholas; Martin, Bryn; Rocque, Brandon et al.
ASME 2013 Summer Bioengineering Conference, SBC 2013. 2013. (ASME 2013 Summer Bioengineering Conference, SBC 2013; Vol. 1 B).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shaffer, N, Martin, B, Rocque, B, Madura, C, Iskandar, B, Wieben, O, Dombrowski, S, Luciano, M, Oshinski, J & Loth, F 2013, Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation. in ASME 2013 Summer Bioengineering Conference, SBC 2013. ASME 2013 Summer Bioengineering Conference, SBC 2013, vol. 1 B, ASME 2013 Summer Bioengineering Conference, SBC 2013, Sunriver, OR, United States, 6/26/13. https://doi.org/10.1115/SBC2013-14808

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abstract = "This study investigates the use of longitudinal impedance (LI) as a means to quantify the severity of Type I Chiari Malformation (CMI). LI was analyzed in image-based models of the cervical spinal subarachnoid space of 22 CMI patients and 10 healthy volunteers. LI was then compared with the cerebellar tonsil herniation (CTH) measured by two neurosurgeons. Results showed that both LI and CTH differentiated CMI patients from healthy volunteers, but lacked the specificity to differentiate symptomatic and asymptomatic patients.",

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AU - Shaffer, Nicholas

AU - Martin, Bryn

AU - Rocque, Brandon

AU - Madura, Casey

AU - Iskandar, Bermans

AU - Wieben, Oliver

AU - Dombrowski, Stephen

AU - Luciano, Mark

AU - Oshinski, John

AU - Loth, Francis

PY - 2013

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N2 - This study investigates the use of longitudinal impedance (LI) as a means to quantify the severity of Type I Chiari Malformation (CMI). LI was analyzed in image-based models of the cervical spinal subarachnoid space of 22 CMI patients and 10 healthy volunteers. LI was then compared with the cerebellar tonsil herniation (CTH) measured by two neurosurgeons. Results showed that both LI and CTH differentiated CMI patients from healthy volunteers, but lacked the specificity to differentiate symptomatic and asymptomatic patients.

AB - This study investigates the use of longitudinal impedance (LI) as a means to quantify the severity of Type I Chiari Malformation (CMI). LI was analyzed in image-based models of the cervical spinal subarachnoid space of 22 CMI patients and 10 healthy volunteers. LI was then compared with the cerebellar tonsil herniation (CTH) measured by two neurosurgeons. Results showed that both LI and CTH differentiated CMI patients from healthy volunteers, but lacked the specificity to differentiate symptomatic and asymptomatic patients.

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BT - ASME 2013 Summer Bioengineering Conference, SBC 2013

T2 - ASME 2013 Summer Bioengineering Conference, SBC 2013

Y2 - 26 June 2013 through 29 June 2013

ER -

Relation of cerebrospinal fluid flow impedance and cerebellar herniation in type i Chiari malformation

Abstract

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