Relation of C-Reactive Protein and New-Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction

Doron Aronson, Monther Boulos, Abeer Suleiman, Salma Bidoosi, Yoram Agmon, Michael Kapeliovich, Rafael Beyar, Walter Markiewicz, Haim Hammerman, Mahmoud Suleiman

Research output: Contribution to journalArticlepeer-review

Abstract

Recent studies have implicated systemic inflammation in the genesis and maintenance of atrial fibrillation (AF). A robust inflammatory response is an integral component of the response to tissue injury during acute myocardial infarction (AMI). However, there is no information concerning the association between inflammation and AF in patients with AMI. We studied 1,209 patients admitted for AMI. C-reactive protein (CRP) was measured by a high-sensitivity assay within 12 to 24 hours after symptom onset. The relation between CRP and new-onset AF occurring during the hospital course and at 1 year was analyzed using multivariable logistic regression and Cox models, respectively. New-onset AF during hospitalization occurred in 6.5%, 10.4%, and 17.1% of patients in the first, second and third CRP tertiles, respectively (p trend

Original languageEnglish (US)
Pages (from-to)753-757
Number of pages5
JournalThe American Journal of Cardiology
Volume100
Issue number5
DOIs
StatePublished - Sep 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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