Relation between the major histocompatibility (B) locus and autoimmune thyroiditis in obese chickens

Larry D. Bacon, Joseph H. Kite, Noel R. Rose

Research output: Contribution to journalArticlepeer-review

Abstract

Obese strain chickens develop circulating autoantibodies to thyroglobulin and lymphocytic infiltration of their thyroids during aging. Two alleles, B 1 and B4, are found with high gene frequency at the major histocompatibility (B) locus. Greater pathology and higher antibody titers are observed in B1B1 and B1B4 birds than in their B4B4 siblings.

Original languageEnglish (US)
Pages (from-to)274-275
Number of pages2
JournalScience
Volume186
Issue number4160
DOIs
StatePublished - Jan 1 1974

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Relation between the major histocompatibility (B) locus and autoimmune thyroiditis in obese chickens'. Together they form a unique fingerprint.

Cite this