Relapsing, remitting hypercortisolism in Cushing's disease due to intratumoral hemorrhages in pituitary microadenoma

Nicholas F. Marko, Amir H. Hamrahian, Betul Hatipoglu, Robert J. Weil

Research output: Contribution to journalArticlepeer-review

Abstract

We report two patients with Cushing's disease (CD) from adrenocorticotropic hormone-secreting microadenomas in whom intralesional hemorrhage caused an episodic, remitting and relapsing pattern of hypercortisolism. To our knowledge this is the first report of patients in whom hemorrhage within a microadenoma caused cyclic CD. Both patients were treated successfully with transsphenoidal surgery.

Original languageEnglish (US)
Pages (from-to)753-756
Number of pages4
JournalJournal of Clinical Neuroscience
Volume20
Issue number5
DOIs
StatePublished - May 2013
Externally publishedYes

Keywords

  • Adrenocorticotropic hormone
  • Apoplexy
  • Cortisol
  • Cushing's syndrome
  • Cyclic Cushing disease
  • Pituitary surgery
  • Transsphenoidal

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Fingerprint

Dive into the research topics of 'Relapsing, remitting hypercortisolism in Cushing's disease due to intratumoral hemorrhages in pituitary microadenoma'. Together they form a unique fingerprint.

Cite this