TY - JOUR
T1 - Regulation of Vascular Reactivity in Scleroderma
T2 - New Insights into Raynaud's Phenomenon
AU - Flavahan, Nicholas A.
N1 - Funding Information:
This article was supported by grants from the NIH (HL080119 and OH008531) and the Peninsula Community Foundation.
PY - 2008/2
Y1 - 2008/2
N2 - Because of the role of the RhoA/Rho kinase (ROCK) pathway in regulating numerous pathologic processes including vasoconstriction, vascular remodeling, and fibrosis, ROCK inhibitors may be especially beneficial in treating Raynaud's phenomenon and scleroderma.
AB - Because of the role of the RhoA/Rho kinase (ROCK) pathway in regulating numerous pathologic processes including vasoconstriction, vascular remodeling, and fibrosis, ROCK inhibitors may be especially beneficial in treating Raynaud's phenomenon and scleroderma.
UR - http://www.scopus.com/inward/record.url?scp=40149105688&partnerID=8YFLogxK
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U2 - 10.1016/j.rdc.2007.12.005
DO - 10.1016/j.rdc.2007.12.005
M3 - Review article
C2 - 18329534
AN - SCOPUS:40149105688
SN - 0889-857X
VL - 34
SP - 81
EP - 87
JO - Rheumatic Disease Clinics of North America
JF - Rheumatic Disease Clinics of North America
IS - 1
ER -