Regulation of production of tumor necrosis factor alpha in monocytes stimulated by the 30-kilodalton antigen of Mycobacterium tuberculosis

L. Averill; Z. Toossi; H. Aung; W. H. Boom; J. J. Ellner

Regulation of production of tumor necrosis factor alpha in monocytes stimulated by the 30-kilodalton antigen of Mycobacterium tuberculosis

L. Averill, Z. Toossi, H. Aung, W. H. Boom, J. J. Ellner

Research output: Contribution to journal › Article › peer-review

Abstract

The 30-kDa secreted antigen of Mycobacterium tuberculosis was a strong inducer of tumor necrosis factor alpha in human monocytes. Our findings suggest that tumor necrosis factor alpha production may be up-regulated at both the posttranscriptional and transcriptional levels. Regulation at the posttranscriptional level probably reflects enhanced translational efficiency.

Original language	English (US)
Pages (from-to)	3206-3208
Number of pages	3
Journal	Infection and Immunity
Volume	63
Issue number	8
State	Published - 1995
Externally published	Yes

ASJC Scopus subject areas

Immunology

Cite this

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title = "Regulation of production of tumor necrosis factor alpha in monocytes stimulated by the 30-kilodalton antigen of Mycobacterium tuberculosis",

abstract = "The 30-kDa secreted antigen of Mycobacterium tuberculosis was a strong inducer of tumor necrosis factor alpha in human monocytes. Our findings suggest that tumor necrosis factor alpha production may be up-regulated at both the posttranscriptional and transcriptional levels. Regulation at the posttranscriptional level probably reflects enhanced translational efficiency.",

author = "L. Averill and Z. Toossi and H. Aung and Boom, {W. H.} and Ellner, {J. J.}",

year = "1995",

language = "English (US)",

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pages = "3206--3208",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

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T1 - Regulation of production of tumor necrosis factor alpha in monocytes stimulated by the 30-kilodalton antigen of Mycobacterium tuberculosis

AU - Averill, L.

AU - Toossi, Z.

AU - Aung, H.

AU - Boom, W. H.

AU - Ellner, J. J.

PY - 1995

Y1 - 1995

N2 - The 30-kDa secreted antigen of Mycobacterium tuberculosis was a strong inducer of tumor necrosis factor alpha in human monocytes. Our findings suggest that tumor necrosis factor alpha production may be up-regulated at both the posttranscriptional and transcriptional levels. Regulation at the posttranscriptional level probably reflects enhanced translational efficiency.

AB - The 30-kDa secreted antigen of Mycobacterium tuberculosis was a strong inducer of tumor necrosis factor alpha in human monocytes. Our findings suggest that tumor necrosis factor alpha production may be up-regulated at both the posttranscriptional and transcriptional levels. Regulation at the posttranscriptional level probably reflects enhanced translational efficiency.

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M3 - Article

C2 - 7622249

AN - SCOPUS:0029102332

SN - 0019-9567

VL - 63

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JO - Infection and Immunity

JF - Infection and Immunity

IS - 8

ER -

Regulation of production of tumor necrosis factor alpha in monocytes stimulated by the 30-kilodalton antigen of Mycobacterium tuberculosis

Abstract

ASJC Scopus subject areas

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