Regulation of intracellular calcium in cardiac muscle

P. H. Backx, Wei Dong Gao, M. D. Azan-Backx, E. Marban, D. Allen, A. Somlyo, A. Landesberg, G. Hasenfuss, S. Sys, David A Kass

Research output: Contribution to journalArticle

Abstract

We have investigated the regulation of intracellular free calcium in heart muscle using the free acid form of the Ca2+ indicator fura-2 iontophoretically microinjected into rat cardiac trabeculae or ferret papillary muscles. This method shows great promise in elucidating a number of crucial questions in cardiac excitation-contraction coupling.

Original languageEnglish (US)
Pages (from-to)3-10
Number of pages8
JournalAdvances in Experimental Medicine and Biology
Volume346
StatePublished - 1993

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Excitation Contraction Coupling
Ferrets
Papillary Muscles
Fura-2
Muscle
Myocardium
Calcium
Acids
Rats

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Backx, P. H., Gao, W. D., Azan-Backx, M. D., Marban, E., Allen, D., Somlyo, A., ... Kass, D. A. (1993). Regulation of intracellular calcium in cardiac muscle. Advances in Experimental Medicine and Biology, 346, 3-10.

Regulation of intracellular calcium in cardiac muscle. / Backx, P. H.; Gao, Wei Dong; Azan-Backx, M. D.; Marban, E.; Allen, D.; Somlyo, A.; Landesberg, A.; Hasenfuss, G.; Sys, S.; Kass, David A.

In: Advances in Experimental Medicine and Biology, Vol. 346, 1993, p. 3-10.

Research output: Contribution to journalArticle

Backx, PH, Gao, WD, Azan-Backx, MD, Marban, E, Allen, D, Somlyo, A, Landesberg, A, Hasenfuss, G, Sys, S & Kass, DA 1993, 'Regulation of intracellular calcium in cardiac muscle', Advances in Experimental Medicine and Biology, vol. 346, pp. 3-10.
Backx PH, Gao WD, Azan-Backx MD, Marban E, Allen D, Somlyo A et al. Regulation of intracellular calcium in cardiac muscle. Advances in Experimental Medicine and Biology. 1993;346:3-10.
Backx, P. H. ; Gao, Wei Dong ; Azan-Backx, M. D. ; Marban, E. ; Allen, D. ; Somlyo, A. ; Landesberg, A. ; Hasenfuss, G. ; Sys, S. ; Kass, David A. / Regulation of intracellular calcium in cardiac muscle. In: Advances in Experimental Medicine and Biology. 1993 ; Vol. 346. pp. 3-10.
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