Regulation of intracellular calcium in cardiac muscle

P. H. Backx, Dong Gao Wei Dong Gao, M. D. Azan-Backx, E. Marban, D. Allen, A. Somlyo, A. Landesberg, G. Hasenfuss, S. Sys, D. Kass

Research output: Contribution to journalArticlepeer-review

Abstract

We have investigated the regulation of intracellular free calcium in heart muscle using the free acid form of the Ca2+ indicator fura-2 iontophoretically microinjected into rat cardiac trabeculae or ferret papillary muscles. This method shows great promise in elucidating a number of crucial questions in cardiac excitation-contraction coupling.

Original languageEnglish (US)
Pages (from-to)3-10
Number of pages8
JournalAdvances in experimental medicine and biology
Volume346
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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