Regulation of DGK-θ

Becky Tu-Sekine, Daniel M. Raben

Research output: Contribution to journalShort survey

Abstract

Diacylglycerol kinases are important regulators of lipid signaling and, consequently, important regulators of many diglyceride-dependent and PA-dependent proteins. Research over the last twenty years has clearly demonstrated that individual DGK isoforms can be connected with disparate cellular processes, indicating the presence of a sophisticated regulatory network for diglyceride and phosphatidic acid signaling through the regulation of individual DGK isoforms. This review presents the progress on the characterization of a primarily neuronal isoform DGK-θ, and examines current data on the primary structure, regulation and potential cellular functions of this enzyme.

Original languageEnglish (US)
Pages (from-to)548-552
Number of pages5
JournalJournal of Cellular Physiology
Volume220
Issue number3
DOIs
StatePublished - Sep 1 2009

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

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