Regulation of CCL2 expression by an upstream TALE homeodomain protein-binding site that synergizes with the site created by the A-2578G SNP

Agriculture & Biology

• chemokine CCL2 100%
• homeodomain proteins 90%
• protein binding 73%
• binding sites 54%
• promoter regions 26%
• alleles 25%
• genetic polymorphism 20%
• inflammation 16%
• dementia 13%
• liver diseases 12%
• chemoattractants 12%
• disease progression 11%
• astrocytes 11%
• tuberculosis 10%
• transcriptional activation 10%
• disease severity 9%
• central nervous system 9%
• chromatin 8%
• macrophages 8%
• binding proteins 7%
• lungs 7%
• transcription factors 7%
• genotype 5%
• assays 4%

Medicine & Life Sciences

• Homeodomain Proteins 87%
• CC Chemokines 81%
• Protein Binding 64%
• Single Nucleotide Polymorphism 54%
• Binding Sites 49%
• Ligands 45%
• Alleles 26%
• AIDS Dementia Complex 13%
• Inflammation 10%
• Chemotactic Factors 10%
• Chromatin Immunoprecipitation 10%
• Pulmonary Tuberculosis 9%
• Astrocytes 8%
• Transcriptional Activation 8%
• Carrier Proteins 7%
• Liver Diseases 7%
• Disease Progression 7%
• Transcription Factors 6%
• Central Nervous System 6%
• Genotype 6%
• Macrophages 6%

Chemical Compounds

• Ligand 28%
• Binding Site 25%
• Protein 15%
• Chemoattractant 13%