Regulation of bradykinin-induced chloride secretion in a human epithelial cell line

D. H. Miller, A. W. Baird, S. Bennet, M. Halushka, M. Sasaguri, H. Schomer, H. S. Margolius

Research output: Contribution to journalArticlepeer-review

Abstract

The chloride secretory response to bradykinin in T84 cells is regulated. The efflux rate of 125I from these cells can be used to measure this response, and to demonstrate that the sensitivity to bradykinin varies with time in culture. The response in NuT84 cells is greater than that in T84, and can be blocked by the B2 receptor antagonist HOE-140.

Original languageEnglish (US)
Pages (from-to)81-86
Number of pages6
JournalAgents and Actions
Volume38
Issue numberSUPPL. II
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)

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