Regulating Antibody Diversity: Taming a Mutagen

Patricia J. Gearhart, Ranjan Sen

Research output: Contribution to journalShort surveypeer-review

Abstract

In a recent issue of Molecular Cell, Conticello et al. (2008) identified a protein that interacts with the activation-induced deaminase protein and affects somatic hypermutation, class switching, and gene conversion in immunoglobulin genes, possibly via the spliceosome transcription complex.

Original languageEnglish (US)
Pages (from-to)615-616
Number of pages2
JournalMolecular cell
Volume31
Issue number5
DOIs
StatePublished - Sep 5 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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