Regression of peripapillary choroidal neovascular membrane in a patient with sarcoidosis after oral steroid therapy

Samir S. Shoughy, Mahmoud O. Jaroudi, Khalid F. Tabbara

Research output: Contribution to journalArticle

Abstract

Choroidal neovascular membrane (CNV) may occur in patients with posterior uveitis. Treatment of patients with corticosteroids induces regression of the inflammation in the posterior pole with downregulation of many cytokines including vascular endothelial growth factors. We report herewith, a case of biopsy proven sarcoidosis that developed posterior uveitis and peripapillary CNV membrane and subretinal hemorrhage with fluid. The patient was treated with systemic steroids. She demonstrated progressive regression of the CNV membrane and complete resolution of the subretinal hemorrhage and fluids. In conclusion, control of the posterior segment inflammation is crucial in the resolution of the CNV membrane in uveitis and the intravitreal anti-vascular endothelial growth factor may not be always indicated.

Original languageEnglish (US)
Pages (from-to)160-162
Number of pages3
JournalSaudi Journal of Ophthalmology
Volume28
Issue number2
DOIs
StatePublished - 2014

Fingerprint

Sarcoidosis
Steroids
Membranes
Posterior Uveitis
Therapeutics
Vascular Endothelial Growth Factors
Hemorrhage
Subretinal Fluid
Inflammation
Uveitis
Vascular Endothelial Growth Factor A
Adrenal Cortex Hormones
Down-Regulation
Cytokines
Biopsy

Keywords

  • Oral steroids
  • Peripapillary CNV
  • Sarcoidosis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Regression of peripapillary choroidal neovascular membrane in a patient with sarcoidosis after oral steroid therapy. / Shoughy, Samir S.; Jaroudi, Mahmoud O.; Tabbara, Khalid F.

In: Saudi Journal of Ophthalmology, Vol. 28, No. 2, 2014, p. 160-162.

Research output: Contribution to journalArticle

Shoughy, Samir S. ; Jaroudi, Mahmoud O. ; Tabbara, Khalid F. / Regression of peripapillary choroidal neovascular membrane in a patient with sarcoidosis after oral steroid therapy. In: Saudi Journal of Ophthalmology. 2014 ; Vol. 28, No. 2. pp. 160-162.
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