Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

S. G. Marcus, P. L. Choyke, R. Reiter, G. S. Jaffe, R. B. Alexander, W. M. Linehan, S. A. Rosenberg, M. M. Walther, A. C. Novick, F. F. Marshall

Research output: Contribution to journalArticle

Abstract

Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.

Original languageEnglish (US)
Pages (from-to)463-466
Number of pages4
JournalJournal of Urology
Volume150
Issue number2
StatePublished - 1993
Externally publishedYes

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Nephrectomy
Renal Cell Carcinoma
Recurrence
Interleukin-2

Keywords

  • carcinoma, renal cell
  • kidney
  • neoplasm metastasis
  • neoplasm regression, spontaneous
  • nephrectomy

ASJC Scopus subject areas

  • Urology

Cite this

Marcus, S. G., Choyke, P. L., Reiter, R., Jaffe, G. S., Alexander, R. B., Linehan, W. M., ... Marshall, F. F. (1993). Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy. Journal of Urology, 150(2), 463-466.

Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy. / Marcus, S. G.; Choyke, P. L.; Reiter, R.; Jaffe, G. S.; Alexander, R. B.; Linehan, W. M.; Rosenberg, S. A.; Walther, M. M.; Novick, A. C.; Marshall, F. F.

In: Journal of Urology, Vol. 150, No. 2, 1993, p. 463-466.

Research output: Contribution to journalArticle

Marcus, SG, Choyke, PL, Reiter, R, Jaffe, GS, Alexander, RB, Linehan, WM, Rosenberg, SA, Walther, MM, Novick, AC & Marshall, FF 1993, 'Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy', Journal of Urology, vol. 150, no. 2, pp. 463-466.
Marcus SG, Choyke PL, Reiter R, Jaffe GS, Alexander RB, Linehan WM et al. Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy. Journal of Urology. 1993;150(2):463-466.
Marcus, S. G. ; Choyke, P. L. ; Reiter, R. ; Jaffe, G. S. ; Alexander, R. B. ; Linehan, W. M. ; Rosenberg, S. A. ; Walther, M. M. ; Novick, A. C. ; Marshall, F. F. / Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy. In: Journal of Urology. 1993 ; Vol. 150, No. 2. pp. 463-466.
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