Regression of metastatic renal cell carcinoma after cytoreductive nephrectomy

S. G. Marcus, P. L. Choyke, R. Reiter, G. S. Jaffe, R. B. Alexander, W. M. Linehan, S. A. Rosenberg, M. M. Walther, A. C. Novick, F. F. Marshall

Research output: Contribution to journalArticlepeer-review

Abstract

Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.

Original languageEnglish (US)
Pages (from-to)463-466
Number of pages4
JournalJournal of Urology
Volume150
Issue number2
DOIs
StatePublished - Jan 1 1993

Keywords

  • carcinoma, renal cell
  • kidney
  • neoplasm metastasis
  • neoplasm regression, spontaneous
  • nephrectomy

ASJC Scopus subject areas

  • Urology

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