Regional localization of histamine and histidine in the brain of the Rhesus monkey

Kenneth M. Taylor, Eduard Gfeller, Solomon H. Snyder

Research output: Contribution to journalArticlepeer-review

Abstract

The development of a sensitive microassay has made possible the evaluation of histamine and histidine concentrations in discrete nuclei and other areas of the rhesus monkey brain. Within the hypothalamus the mammillary bodies and the supraoptic nucleus contained the highest concentration of histamine, which was about 4 times that found in the preoptic and paraventricular nuclei. In most brain regions the medially located portions contained more histamine than did the lateral areas. There was no correlation between histamine and histidine concentrations in most areas of the brain. Histidine was more uniformly distributed and generally occurred in concentrations 100 times those of histamine.

Original languageEnglish (US)
Pages (from-to)171-179
Number of pages9
JournalBrain research
Volume41
Issue number1
DOIs
StatePublished - Jun 8 1972

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Regional localization of histamine and histidine in the brain of the Rhesus monkey'. Together they form a unique fingerprint.

Cite this