Regional left ventricular function in individuals with mild to moderate renal insufficiency: The Multi-Ethnic Study of Atherosclerosis

Khurram Nasir, Boaz D. Rosen, Holly J. Kramer, Thor Edvardsen, David A. Bluemke, Kiang Liu, Joao Lima

Research output: Contribution to journalArticle

Abstract

Introduction: Asymptomatic individuals with moderate reduction in renal function are at increased risk for congestive heart failure. In this study we investigate the relationship between mild-moderate renal insufficiency and regional left ventricle function in a population free of cardiovascular disease. Method: This is a cross-sectional study in 500 individuals ≥45 years of age without known cardiovascular disease who participated in the Multi-Ethnic Study of Atherosclerosis. Regional systolic and diastolic strain rate as well as peak systolic midwall circumferential strain were calculated from tagged magnetic resonance imaging studies in these participants. Regions were defined by coronary territories (left anterior descending, left circumflex, right coronary artery). Creatinine clearance (CrCl) was estimated by using the Cockcroft-Gault equation and categorized as ≥90 mL/min (normal CrCl), 60 to 89 mL/min (mildly reduced CrCl), and

Original languageEnglish (US)
Pages (from-to)545-551
Number of pages7
JournalAmerican Heart Journal
Volume153
Issue number4
DOIs
StatePublished - Apr 2007

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Left Ventricular Function
Renal Insufficiency
Creatinine
Atherosclerosis
Cardiovascular Diseases
Heart Ventricles
Coronary Vessels
Heart Failure
Cross-Sectional Studies
Magnetic Resonance Imaging
Kidney
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Regional left ventricular function in individuals with mild to moderate renal insufficiency : The Multi-Ethnic Study of Atherosclerosis. / Nasir, Khurram; Rosen, Boaz D.; Kramer, Holly J.; Edvardsen, Thor; Bluemke, David A.; Liu, Kiang; Lima, Joao.

In: American Heart Journal, Vol. 153, No. 4, 04.2007, p. 545-551.

Research output: Contribution to journalArticle

Nasir, Khurram ; Rosen, Boaz D. ; Kramer, Holly J. ; Edvardsen, Thor ; Bluemke, David A. ; Liu, Kiang ; Lima, Joao. / Regional left ventricular function in individuals with mild to moderate renal insufficiency : The Multi-Ethnic Study of Atherosclerosis. In: American Heart Journal. 2007 ; Vol. 153, No. 4. pp. 545-551.
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