Regional cardiac function assessment in 4D CT: comparison between SQUEEZ and ejection fraction.

Amir Pourmorteza, Karl H. Schuleri, Daniel Herzka, Albert C. Lardo, Elliot R. McVeigh

Research output: Contribution to journalArticle

Abstract

Recent advances in computed tomography (CT) imaging technology allow fine anatomical structures such as endocardial trabeculae to be resolved. We have developed a method to detect and track such features on the endocardium to extract a measure that reflects local myocardial contraction with minimal human operator interaction. The relative motion of these surface features were used to represent the local contraction of the endocardial surface with a metric we termed "stretch quantifier of endocardial engraved zones" (SQUEEZ). The results were compared against CT function analysis software available through the scanner vendor. SQUEEZ showed significant difference between infarct and remote regions (p<0.0001) as verified by delayed enhanced magnetic resonance imaging. The vendor software showed inferior spatial resolution and stair-step artifacts in regional function maps.

Fingerprint

Four-Dimensional Computed Tomography
Tomography
Software
Myocardial Contraction
Imaging techniques
Endocardium
Stairs
Magnetic resonance
Artifacts
Magnetic Resonance Imaging
Technology

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

@article{ce236ccb581f429ca8b04a88bd8e0acc,
title = "Regional cardiac function assessment in 4D CT: comparison between SQUEEZ and ejection fraction.",
abstract = "Recent advances in computed tomography (CT) imaging technology allow fine anatomical structures such as endocardial trabeculae to be resolved. We have developed a method to detect and track such features on the endocardium to extract a measure that reflects local myocardial contraction with minimal human operator interaction. The relative motion of these surface features were used to represent the local contraction of the endocardial surface with a metric we termed {"}stretch quantifier of endocardial engraved zones{"} (SQUEEZ). The results were compared against CT function analysis software available through the scanner vendor. SQUEEZ showed significant difference between infarct and remote regions (p<0.0001) as verified by delayed enhanced magnetic resonance imaging. The vendor software showed inferior spatial resolution and stair-step artifacts in regional function maps.",
author = "Amir Pourmorteza and Schuleri, {Karl H.} and Daniel Herzka and Lardo, {Albert C.} and McVeigh, {Elliot R.}",
year = "2012",
language = "English (US)",
volume = "2012",
pages = "4966--4969",
journal = "Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference",
issn = "1557-170X",
publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - JOUR

T1 - Regional cardiac function assessment in 4D CT

T2 - comparison between SQUEEZ and ejection fraction.

AU - Pourmorteza, Amir

AU - Schuleri, Karl H.

AU - Herzka, Daniel

AU - Lardo, Albert C.

AU - McVeigh, Elliot R.

PY - 2012

Y1 - 2012

N2 - Recent advances in computed tomography (CT) imaging technology allow fine anatomical structures such as endocardial trabeculae to be resolved. We have developed a method to detect and track such features on the endocardium to extract a measure that reflects local myocardial contraction with minimal human operator interaction. The relative motion of these surface features were used to represent the local contraction of the endocardial surface with a metric we termed "stretch quantifier of endocardial engraved zones" (SQUEEZ). The results were compared against CT function analysis software available through the scanner vendor. SQUEEZ showed significant difference between infarct and remote regions (p<0.0001) as verified by delayed enhanced magnetic resonance imaging. The vendor software showed inferior spatial resolution and stair-step artifacts in regional function maps.

AB - Recent advances in computed tomography (CT) imaging technology allow fine anatomical structures such as endocardial trabeculae to be resolved. We have developed a method to detect and track such features on the endocardium to extract a measure that reflects local myocardial contraction with minimal human operator interaction. The relative motion of these surface features were used to represent the local contraction of the endocardial surface with a metric we termed "stretch quantifier of endocardial engraved zones" (SQUEEZ). The results were compared against CT function analysis software available through the scanner vendor. SQUEEZ showed significant difference between infarct and remote regions (p<0.0001) as verified by delayed enhanced magnetic resonance imaging. The vendor software showed inferior spatial resolution and stair-step artifacts in regional function maps.

UR - http://www.scopus.com/inward/record.url?scp=84880948243&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880948243&partnerID=8YFLogxK

M3 - Article

C2 - 23367042

AN - SCOPUS:84880948243

VL - 2012

SP - 4966

EP - 4969

JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference

SN - 1557-170X

ER -