Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6

George J. Pappas; Mihael H. Polymeropoulos; John M. Boyle; Jeffrey M. Trent

doi:10.1016/0888-7543(95)80117-5

Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6

George J. Pappas, Mihael H. Polymeropoulos, John M. Boyle, Jeffrey M. Trent

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

Original language	English (US)
Pages (from-to)	124-129
Number of pages	6
Journal	Genomics
Volume	25
Issue number	1
DOIs	https://doi.org/10.1016/0888-7543(95)80117-5
State	Published - Jan 1 1995
Externally published	Yes

ASJC Scopus subject areas

Genetics

Access to Document

10.1016/0888-7543(95)80117-5

Cite this

@article{fc2aa4b2b6c04294a326f89332f02c87,

title = "Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6",

abstract = "We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.",

author = "Pappas, {George J.} and Polymeropoulos, {Mihael H.} and Boyle, {John M.} and Trent, {Jeffrey M.}",

year = "1995",

month = jan,

day = "1",

doi = "10.1016/0888-7543(95)80117-5",

language = "English (US)",

volume = "25",

pages = "124--129",

journal = "Genomics",

issn = "0888-7543",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6

AU - Pappas, George J.

AU - Polymeropoulos, Mihael H.

AU - Boyle, John M.

AU - Trent, Jeffrey M.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

AB - We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

UR - http://www.scopus.com/inward/record.url?scp=0028900763&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028900763&partnerID=8YFLogxK

U2 - 10.1016/0888-7543(95)80117-5

DO - 10.1016/0888-7543(95)80117-5

M3 - Article

C2 - 7774909

AN - SCOPUS:0028900763

SN - 0888-7543

VL - 25

SP - 124

EP - 129

JO - Genomics

JF - Genomics

IS - 1

ER -

Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this