Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6

George J. Pappas, Mihael H. Polymeropoulos, John M. Boyle, Jeffrey M. Trent

Research output: Contribution to journalArticle

Abstract

We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

Original languageEnglish (US)
Pages (from-to)124-129
Number of pages6
JournalGenomics
Volume25
Issue number1
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 6
Expressed Sequence Tags
Human Chromosomes
Genes
Sequence Analysis
Rodentia
Complementary DNA
Chromosomes
Polymerase Chain Reaction
Brain

ASJC Scopus subject areas

  • Genetics

Cite this

Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6. / Pappas, George J.; Polymeropoulos, Mihael H.; Boyle, John M.; Trent, Jeffrey M.

In: Genomics, Vol. 25, No. 1, 01.01.1995, p. 124-129.

Research output: Contribution to journalArticle

Pappas, George J. ; Polymeropoulos, Mihael H. ; Boyle, John M. ; Trent, Jeffrey M. / Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6. In: Genomics. 1995 ; Vol. 25, No. 1. pp. 124-129.
@article{fc2aa4b2b6c04294a326f89332f02c87,
title = "Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6",
abstract = "We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.",
author = "Pappas, {George J.} and Polymeropoulos, {Mihael H.} and Boyle, {John M.} and Trent, {Jeffrey M.}",
year = "1995",
month = "1",
day = "1",
doi = "10.1016/0888-7543(95)80117-5",
language = "English (US)",
volume = "25",
pages = "124--129",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Regional assignment by hybrid mapping of 36 expressed sequence tags (ESTs) on human chromosome 6

AU - Pappas, George J.

AU - Polymeropoulos, Mihael H.

AU - Boyle, John M.

AU - Trent, Jeffrey M.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

AB - We have determined the regional chromosome assignment of 36 cDNAs from infant brain libraries by assessing the concordant segregation of PCR products using a human-rodent hybrid mapping panel that subdivides chromosome 6 into 15 regions. These mapped sequences serve as markers for the physical and expression maps of chromosome 6, as well as candidate genes for various disease loci. Sequence analysis has identified putative functions and motifs for some of these genes.

UR - http://www.scopus.com/inward/record.url?scp=0028900763&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028900763&partnerID=8YFLogxK

U2 - 10.1016/0888-7543(95)80117-5

DO - 10.1016/0888-7543(95)80117-5

M3 - Article

C2 - 7774909

AN - SCOPUS:0028900763

VL - 25

SP - 124

EP - 129

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 1

ER -