Reference values of tricuspid annular peak systolic velocity in healthy pediatric patients, calculation of Z score, and comparison to tricuspid annular plane systolic excursion

Martin Koestenberger, Bert Nagel, William Ravekes, Alexander Avian, Bernd Heinzl, Gerhard Cvirn, Peter Fritsch, Andrea Fandl, Thomas Rehak, Andreas Gamillscheg

Research output: Contribution to journalArticlepeer-review

Abstract

The tricuspid annular peak systolic velocity (TAPSV) is an echocardiographic measurement assessing right ventricular systolic function in children and adults. We determined the growth-related changes of the TAPSV to establish the references values for the entire pediatric age group. A prospective study was conducted of a group of 860 healthy pediatric patients (age 1 day to 18 years; body surface area [BSA] 0.14 to 2.30 m 2). We determined the effects of age, gender, and BSA on the TAPSV values. Stepwise linear multiple regression analysis was used to estimate the TAPSV from the age, BSA, and gender. A correlation of normal TAPSV with normal tricuspid annular plane systolic excursion values was performed. The TAPSV ranged from a mean of 7.2 cm/s (z score ± 2: 4.8 to 9.5 cm/s) in the newborn to 14.3 cm/s (z score ± 2: 10.6 to 18.6 cm/s) in the 18-year-old adolescent. The TAPSV values showed a positive correlation with age and BSA, with a nonlinear course. No significant difference was found in the TAPSV values according to gender. A significant correlation was found between the TAPSV and tricuspid annular plane systolic excursion values in our pediatric population. In conclusion, the z scores of the TAPSV values were calculated, and percentile charts were established to serve as reference data for patients with congenital heart disease.

Original languageEnglish (US)
Pages (from-to)116-121
Number of pages6
JournalAmerican Journal of Cardiology
Volume109
Issue number1
DOIs
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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