TY - JOUR
T1 - Reference values of the right ventricular outflow tract systolic excursion in 711 healthy children and calculation of Z-score values
AU - Koestenberger, Martin
AU - Ravekes, William
AU - Nagel, Bert
AU - Avian, Alexander
AU - Heinzl, Bernd
AU - Cvirn, Gerhard
AU - Fritsch, Peter
AU - Fandl, Andrea
AU - Rehak, Thomas
AU - Gamillscheg, Andreas
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/9
Y1 - 2014/9
N2 - Objective Quantitative determination of right ventricular (RV) function has gained moreinterest over the last years.TheRVoutflow tract systolic excursion (RVOT SE) has been recently proposed as an echocardiographic tool to assess RV systolic function in adults.We aimed to determine growth-related changes of RVOT SE in children and to establish references values. Study design A prospective studywas conducted in a group of 711 healthy paediatric patients (age: 1 day to 18 years).We determined the effects of age and body surface area (BSA) on RVOT SE values. RVOT SE values were further correlated with the established RV systolic function parameters tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (S'). Results The RVOT SE ranged from a mean of 3.4 mm in neonates to 9.5 mm in 18-year-old adolescents. The RVOT SE values showed a positive correlation with age (r = 0.90, P< 0.001) and BSA (r = 0.91, P< 0.001). A significant positive correlation was seen between RVOT SE and TAPSE (r = 0.93, P< 0.001) and also between RVOT SE and S' (r = 0.86, P< 0.001) in our patients. Conclusion RVOT SE provides a simple measure and, in combination with long-axis excursion parameters TAPSE and S', a comprehensive assessment of RV systolic function. Z-scores of RVOT SE values were calculated, and percentile charts were established to serve as reference data.
AB - Objective Quantitative determination of right ventricular (RV) function has gained moreinterest over the last years.TheRVoutflow tract systolic excursion (RVOT SE) has been recently proposed as an echocardiographic tool to assess RV systolic function in adults.We aimed to determine growth-related changes of RVOT SE in children and to establish references values. Study design A prospective studywas conducted in a group of 711 healthy paediatric patients (age: 1 day to 18 years).We determined the effects of age and body surface area (BSA) on RVOT SE values. RVOT SE values were further correlated with the established RV systolic function parameters tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (S'). Results The RVOT SE ranged from a mean of 3.4 mm in neonates to 9.5 mm in 18-year-old adolescents. The RVOT SE values showed a positive correlation with age (r = 0.90, P< 0.001) and BSA (r = 0.91, P< 0.001). A significant positive correlation was seen between RVOT SE and TAPSE (r = 0.93, P< 0.001) and also between RVOT SE and S' (r = 0.86, P< 0.001) in our patients. Conclusion RVOT SE provides a simple measure and, in combination with long-axis excursion parameters TAPSE and S', a comprehensive assessment of RV systolic function. Z-scores of RVOT SE values were calculated, and percentile charts were established to serve as reference data.
KW - Age
KW - Body surface area
KW - Paediatric patients
KW - Reference values
KW - Right ventricular outflow tract systolic excursion
KW - Right ventricular systolic function
KW - Z-score
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U2 - 10.1093/ehjci/jeu041
DO - 10.1093/ehjci/jeu041
M3 - Article
C2 - 24662442
AN - SCOPUS:84906807770
VL - 15
SP - 980
EP - 986
JO - European Heart Journal Cardiovascular Imaging
JF - European Heart Journal Cardiovascular Imaging
SN - 2047-2404
IS - 9
ER -