Reference values of the right ventricular outflow tract systolic excursion in 711 healthy children and calculation of Z-score values

Martin Koestenberger, William Ravekes, Bert Nagel, Alexander Avian, Bernd Heinzl, Gerhard Cvirn, Peter Fritsch, Andrea Fandl, Thomas Rehak, Andreas Gamillscheg

Research output: Contribution to journalArticle

Abstract

Objective Quantitative determination of right ventricular (RV) function has gained moreinterest over the last years.TheRVoutflow tract systolic excursion (RVOT SE) has been recently proposed as an echocardiographic tool to assess RV systolic function in adults.We aimed to determine growth-related changes of RVOT SE in children and to establish references values. Study design A prospective studywas conducted in a group of 711 healthy paediatric patients (age: 1 day to 18 years).We determined the effects of age and body surface area (BSA) on RVOT SE values. RVOT SE values were further correlated with the established RV systolic function parameters tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (S'). Results The RVOT SE ranged from a mean of 3.4 mm in neonates to 9.5 mm in 18-year-old adolescents. The RVOT SE values showed a positive correlation with age (r = 0.90, P<0.001) and BSA (r = 0.91, P<0.001). A significant positive correlation was seen between RVOT SE and TAPSE (r = 0.93, P<0.001) and also between RVOT SE and S' (r = 0.86, P<0.001) in our patients. Conclusion RVOT SE provides a simple measure and, in combination with long-axis excursion parameters TAPSE and S', a comprehensive assessment of RV systolic function. Z-scores of RVOT SE values were calculated, and percentile charts were established to serve as reference data.

Original languageEnglish (US)
Pages (from-to)980-986
Number of pages7
JournalEuropean Heart Journal Cardiovascular Imaging
Volume15
Issue number9
DOIs
StatePublished - 2014

Fingerprint

Right Ventricular Function
Reference Values
Body Surface Area
Newborn Infant
Pediatrics
Growth

Keywords

  • Age
  • Body surface area
  • Paediatric patients
  • Reference values
  • Right ventricular outflow tract systolic excursion
  • Right ventricular systolic function
  • Z-score

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Reference values of the right ventricular outflow tract systolic excursion in 711 healthy children and calculation of Z-score values. / Koestenberger, Martin; Ravekes, William; Nagel, Bert; Avian, Alexander; Heinzl, Bernd; Cvirn, Gerhard; Fritsch, Peter; Fandl, Andrea; Rehak, Thomas; Gamillscheg, Andreas.

In: European Heart Journal Cardiovascular Imaging, Vol. 15, No. 9, 2014, p. 980-986.

Research output: Contribution to journalArticle

Koestenberger, Martin ; Ravekes, William ; Nagel, Bert ; Avian, Alexander ; Heinzl, Bernd ; Cvirn, Gerhard ; Fritsch, Peter ; Fandl, Andrea ; Rehak, Thomas ; Gamillscheg, Andreas. / Reference values of the right ventricular outflow tract systolic excursion in 711 healthy children and calculation of Z-score values. In: European Heart Journal Cardiovascular Imaging. 2014 ; Vol. 15, No. 9. pp. 980-986.
@article{55ce4f483d75411280395e9d8877f0b3,
title = "Reference values of the right ventricular outflow tract systolic excursion in 711 healthy children and calculation of Z-score values",
abstract = "Objective Quantitative determination of right ventricular (RV) function has gained moreinterest over the last years.TheRVoutflow tract systolic excursion (RVOT SE) has been recently proposed as an echocardiographic tool to assess RV systolic function in adults.We aimed to determine growth-related changes of RVOT SE in children and to establish references values. Study design A prospective studywas conducted in a group of 711 healthy paediatric patients (age: 1 day to 18 years).We determined the effects of age and body surface area (BSA) on RVOT SE values. RVOT SE values were further correlated with the established RV systolic function parameters tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (S'). Results The RVOT SE ranged from a mean of 3.4 mm in neonates to 9.5 mm in 18-year-old adolescents. The RVOT SE values showed a positive correlation with age (r = 0.90, P<0.001) and BSA (r = 0.91, P<0.001). A significant positive correlation was seen between RVOT SE and TAPSE (r = 0.93, P<0.001) and also between RVOT SE and S' (r = 0.86, P<0.001) in our patients. Conclusion RVOT SE provides a simple measure and, in combination with long-axis excursion parameters TAPSE and S', a comprehensive assessment of RV systolic function. Z-scores of RVOT SE values were calculated, and percentile charts were established to serve as reference data.",
keywords = "Age, Body surface area, Paediatric patients, Reference values, Right ventricular outflow tract systolic excursion, Right ventricular systolic function, Z-score",
author = "Martin Koestenberger and William Ravekes and Bert Nagel and Alexander Avian and Bernd Heinzl and Gerhard Cvirn and Peter Fritsch and Andrea Fandl and Thomas Rehak and Andreas Gamillscheg",
year = "2014",
doi = "10.1093/ehjci/jeu041",
language = "English (US)",
volume = "15",
pages = "980--986",
journal = "European Heart Journal Cardiovascular Imaging",
issn = "2047-2404",
publisher = "Oxford University Press",
number = "9",

}

TY - JOUR

T1 - Reference values of the right ventricular outflow tract systolic excursion in 711 healthy children and calculation of Z-score values

AU - Koestenberger, Martin

AU - Ravekes, William

AU - Nagel, Bert

AU - Avian, Alexander

AU - Heinzl, Bernd

AU - Cvirn, Gerhard

AU - Fritsch, Peter

AU - Fandl, Andrea

AU - Rehak, Thomas

AU - Gamillscheg, Andreas

PY - 2014

Y1 - 2014

N2 - Objective Quantitative determination of right ventricular (RV) function has gained moreinterest over the last years.TheRVoutflow tract systolic excursion (RVOT SE) has been recently proposed as an echocardiographic tool to assess RV systolic function in adults.We aimed to determine growth-related changes of RVOT SE in children and to establish references values. Study design A prospective studywas conducted in a group of 711 healthy paediatric patients (age: 1 day to 18 years).We determined the effects of age and body surface area (BSA) on RVOT SE values. RVOT SE values were further correlated with the established RV systolic function parameters tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (S'). Results The RVOT SE ranged from a mean of 3.4 mm in neonates to 9.5 mm in 18-year-old adolescents. The RVOT SE values showed a positive correlation with age (r = 0.90, P<0.001) and BSA (r = 0.91, P<0.001). A significant positive correlation was seen between RVOT SE and TAPSE (r = 0.93, P<0.001) and also between RVOT SE and S' (r = 0.86, P<0.001) in our patients. Conclusion RVOT SE provides a simple measure and, in combination with long-axis excursion parameters TAPSE and S', a comprehensive assessment of RV systolic function. Z-scores of RVOT SE values were calculated, and percentile charts were established to serve as reference data.

AB - Objective Quantitative determination of right ventricular (RV) function has gained moreinterest over the last years.TheRVoutflow tract systolic excursion (RVOT SE) has been recently proposed as an echocardiographic tool to assess RV systolic function in adults.We aimed to determine growth-related changes of RVOT SE in children and to establish references values. Study design A prospective studywas conducted in a group of 711 healthy paediatric patients (age: 1 day to 18 years).We determined the effects of age and body surface area (BSA) on RVOT SE values. RVOT SE values were further correlated with the established RV systolic function parameters tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (S'). Results The RVOT SE ranged from a mean of 3.4 mm in neonates to 9.5 mm in 18-year-old adolescents. The RVOT SE values showed a positive correlation with age (r = 0.90, P<0.001) and BSA (r = 0.91, P<0.001). A significant positive correlation was seen between RVOT SE and TAPSE (r = 0.93, P<0.001) and also between RVOT SE and S' (r = 0.86, P<0.001) in our patients. Conclusion RVOT SE provides a simple measure and, in combination with long-axis excursion parameters TAPSE and S', a comprehensive assessment of RV systolic function. Z-scores of RVOT SE values were calculated, and percentile charts were established to serve as reference data.

KW - Age

KW - Body surface area

KW - Paediatric patients

KW - Reference values

KW - Right ventricular outflow tract systolic excursion

KW - Right ventricular systolic function

KW - Z-score

UR - http://www.scopus.com/inward/record.url?scp=84906807770&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84906807770&partnerID=8YFLogxK

U2 - 10.1093/ehjci/jeu041

DO - 10.1093/ehjci/jeu041

M3 - Article

C2 - 24662442

AN - SCOPUS:84906807770

VL - 15

SP - 980

EP - 986

JO - European Heart Journal Cardiovascular Imaging

JF - European Heart Journal Cardiovascular Imaging

SN - 2047-2404

IS - 9

ER -