Abstract
Background: The mitral annular peak systolic velocity (Sm) is an echocardiographic measurement using tissue Doppler imaging to assess longitudinal left ventricular (LV) systolic function in children and adults. We determined growth-related changes in Sm to establish reference values for the entire pediatric age group. Methods and Results: A prospective study was conducted in a group of 690 healthy pediatric patients (age: 1 day-18 years). We determined the effects of age, sex, and body surface area (BSA) on the Sm values. Regression analysis was used to estimate Sm from age, BSA, and sex. In addition, a correlation of normal Sm with normal age-matched values of the M-mode parameter mitral annular plane systolic excursion (MAPSE) was measured. The Sm ranged from a mean of 5.8 cm/sec (Z-score ±2: 3.6-8.0 cm/sec) in the newborn to 11.8 cm/sec (Z-score ±2: 8.5-15.1 cm/sec) in the 18-year-old adolescent. The Sm values showed a positive correlation with age and BSA with a nonlinear course. There was no significant difference in Sm values between females and males. A significant correlation was found between Sm and MAPSE values. Conclusion: Z-scores of Sm values were calculated and percentile charts were established to serve as reference data in patients with congenital heart diseases. (Echocardiography 2014;31:1122-1130).
Original language | English (US) |
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Pages (from-to) | 1122-1130 |
Number of pages | 9 |
Journal | Echocardiography |
Volume | 31 |
Issue number | 9 |
DOIs | |
State | Published - 2014 |
Keywords
- Left ventricular systolic function
- Mitral annular peak systolic velocity
- Mitral annular plane systolic excursion
- Pediatric patients
- Reference values
- Z-score
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine