Reference values and factors associated with renal resistive index in a family-based population study

Belén Ponte, Menno Pruijm, Daniel Ackermann, Philippe Vuistiner, Ute Eisenberger, Idris Guessous, Valentin Rousson, Markus G. Mohaupt, Heba Alwan, Georg Ehret, Antoinette Pechere-Bertschi, Fred Paccaud, Jan A. Staessen, Bruno Vogt, Michel Burnier, Pierre Yves Martin, Murielle Bochud

Research output: Contribution to journalArticle

Abstract

Increased renal resistive index (RRI) has been recently associated with target organ damage and cardiovascular or renal outcomes in patients with hypertension and diabetes mellitus. However, reference values in the general population and information on familial aggregation are largely lacking. We determined the distribution of RRI, associated factors, and heritability in a population-based study. Families of European ancestry were randomly selected in 3 Swiss cities. Anthropometric parameters and cardiovascular risk factors were assessed. A renal Doppler ultrasound was performed, and RRI was measured in 3 segmental arteries of both kidneys. We used multilevel linear regression analysis to explore the factors associated with RRI, adjusting for center and family relationships. Sex-specific reference values for RRI were generated according to age. Heritability was estimated by variance components using the ASSOC program (SAGE software). Four hundred women (mean age±SD, 44.9±16.7 years) and 326 men (42.1±16.8 years) with normal renal ultrasound had mean RRI of 0.64±0.05 and 0.62±0.05, respectively (P

Original languageEnglish (US)
Pages (from-to)136-142
Number of pages7
JournalHypertension
Volume63
Issue number1
DOIs
StatePublished - Jan 2014
Externally publishedYes

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Reference Values
Kidney
Population
Doppler Ultrasonography
Family Relations
Linear Models
Diabetes Mellitus
Software
Arteries
Regression Analysis
Hypertension

Keywords

  • Reference values
  • Ultrasonography

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Ponte, B., Pruijm, M., Ackermann, D., Vuistiner, P., Eisenberger, U., Guessous, I., ... Bochud, M. (2014). Reference values and factors associated with renal resistive index in a family-based population study. Hypertension, 63(1), 136-142. https://doi.org/10.1161/HYPERTENSIONAHA.113.02321

Reference values and factors associated with renal resistive index in a family-based population study. / Ponte, Belén; Pruijm, Menno; Ackermann, Daniel; Vuistiner, Philippe; Eisenberger, Ute; Guessous, Idris; Rousson, Valentin; Mohaupt, Markus G.; Alwan, Heba; Ehret, Georg; Pechere-Bertschi, Antoinette; Paccaud, Fred; Staessen, Jan A.; Vogt, Bruno; Burnier, Michel; Martin, Pierre Yves; Bochud, Murielle.

In: Hypertension, Vol. 63, No. 1, 01.2014, p. 136-142.

Research output: Contribution to journalArticle

Ponte, B, Pruijm, M, Ackermann, D, Vuistiner, P, Eisenberger, U, Guessous, I, Rousson, V, Mohaupt, MG, Alwan, H, Ehret, G, Pechere-Bertschi, A, Paccaud, F, Staessen, JA, Vogt, B, Burnier, M, Martin, PY & Bochud, M 2014, 'Reference values and factors associated with renal resistive index in a family-based population study', Hypertension, vol. 63, no. 1, pp. 136-142. https://doi.org/10.1161/HYPERTENSIONAHA.113.02321
Ponte, Belén ; Pruijm, Menno ; Ackermann, Daniel ; Vuistiner, Philippe ; Eisenberger, Ute ; Guessous, Idris ; Rousson, Valentin ; Mohaupt, Markus G. ; Alwan, Heba ; Ehret, Georg ; Pechere-Bertschi, Antoinette ; Paccaud, Fred ; Staessen, Jan A. ; Vogt, Bruno ; Burnier, Michel ; Martin, Pierre Yves ; Bochud, Murielle. / Reference values and factors associated with renal resistive index in a family-based population study. In: Hypertension. 2014 ; Vol. 63, No. 1. pp. 136-142.
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