Reduction of epididymal sperm motility after ablation of the inferior mesenteric plexus in the rat

K. L. Billups, S. L. Tillman, T. S.K. Chang

Research output: Contribution to journalArticle

Abstract

Surgical ablation of the inferior mesenteric plexus in the rat results in an excessive accumulation of sperm within the cauda epididymidis. The present study examined the effect of ablation of the inferior mesenteric plexus on the motility of cauda epididymal spermatozoa. One to 8 weeks after ablation of the inferior mesenteric plexus, sperm curvilinear and straight line swimming velocities were reduced significantly compared with sperm curvilinear and straight line swimming velocities from sham-operated controls. Sperm swimming linearity also changed significantly versus controls after inferior mesenteric plexus ablation. Additional experiments using a vasectomy model suggested that the reductions in sperm curvilinear and straight swimming velocities after inferior mesenteric plexus ablation were not primarily the result of tubal obstruction. These data suggest that the sympathetic nervous system may influence epididymal sperm function.

Original languageEnglish (US)
Pages (from-to)1076-1082
Number of pages7
JournalFertility and sterility
Volume53
Issue number6
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Reduction of epididymal sperm motility after ablation of the inferior mesenteric plexus in the rat'. Together they form a unique fingerprint.

  • Cite this