Reduction of cholera in Bangladeshi villages by simple filtration

Rita R. Colwell, Anwar Huq, M. Sirajul Islam, K. M.A. Aziz, M. Yunus, N. Huda Khan, A. Mahmud, R. Bradley Sack, G. B. Nair, J. Chakraborty, David A. Sack, E. Russek-Cohen

Research output: Contribution to journalArticlepeer-review


Based on results of ecological studies demonstrating that Vibrio cholerae, the etiological agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple filtration procedure was developed whereby zooplankton, most phytoplankton, and particulates >20 μm were removed from water before use. Effective deployment of this filtration procedure, from September 1999 through July 2002 in 65 villages of rural Bangladesh, of which the total population for the entire study comprised ≈133,000 individuals, yielded a 48% reduction in cholera (P < 0.005) compared with the control.

Original languageEnglish (US)
Pages (from-to)1051-1055
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number3
StatePublished - Feb 4 2003
Externally publishedYes

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