Reduction of Biliverdin-C14 to Bilirubin-C14 in vivo

Gary W. Goldstein, Roger Lester

Research output: Contribution to journalArticlepeer-review

Abstract

Radiochemically pure biliverdin-C14 was administered intravenously to rats prepared with an external biliary fistula. A major fraction of the pigment was rapidly reduced to bilirubin and was recovered from the bile as conjugated bilirubin-C14. The results are consistent with the view that bili-verdin may be an intermediate in the degradation of hemoglobin to bilirubin.

Original languageEnglish (US)
Pages (from-to)681-683
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume117
Issue number3
DOIs
StatePublished - Dec 1964
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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