Reducing Clot Burden for Intracerebral Hemorrhage and Intraventricular Hemorrhage

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Spontaneous intracerebral hemorrhage (ICH) is a disabling neurologic injury and can lead to multiple complications, including edema, intraventricular hemorrhage (IVH), and hydrocephalus. As both hematoma volume and perihematomal edema are predictive of functional outcome in ICH, neurointensivists and neurosurgeons have evaluated ways to reduce clot burden and edema expansion. In this chapter, we review recent evidence from the Minimally Invasive Surgery and rt-PA in Intracerebral Hemorrhage Evacuation phase III (MISTIE III) trial as well as the Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR IVH) trial in order to provide insight regarding surgical clot evacuation and IVH fibrinolysis, respectively.

Original languageEnglish (US)
Title of host publicationCurrent Clinical Neurology
PublisherHumana Press Inc.
Pages361-367
Number of pages7
DOIs
StatePublished - 2020

Publication series

NameCurrent Clinical Neurology
ISSN (Print)1559-0585
ISSN (Electronic)2524-4043

Keywords

  • CLEAR
  • Hydrocephalus
  • Intracerebral hemorrhage
  • Intraventricular hemorrhage
  • MISTIE
  • Perihematomal edema
  • STICH

ASJC Scopus subject areas

  • Clinical Neurology

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