@inbook{c0e5e604c5344fdfb1b96bfbe9d4c1c7,
title = "Reducing Clot Burden for Intracerebral Hemorrhage and Intraventricular Hemorrhage",
abstract = "Spontaneous intracerebral hemorrhage (ICH) is a disabling neurologic injury and can lead to multiple complications, including edema, intraventricular hemorrhage (IVH), and hydrocephalus. As both hematoma volume and perihematomal edema are predictive of functional outcome in ICH, neurointensivists and neurosurgeons have evaluated ways to reduce clot burden and edema expansion. In this chapter, we review recent evidence from the Minimally Invasive Surgery and rt-PA in Intracerebral Hemorrhage Evacuation phase III (MISTIE III) trial as well as the Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage (CLEAR IVH) trial in order to provide insight regarding surgical clot evacuation and IVH fibrinolysis, respectively.",
keywords = "CLEAR, Hydrocephalus, Intracerebral hemorrhage, Intraventricular hemorrhage, MISTIE, Perihematomal edema, STICH",
author = "Shin, {Samuel S.} and Nyquist, {Paul A.} and Ziai, {Wendy C.}",
note = "Publisher Copyright: {\textcopyright} 2020, Springer Nature Switzerland AG.",
year = "2020",
doi = "10.1007/978-3-030-36548-6_26",
language = "English (US)",
series = "Current Clinical Neurology",
publisher = "Humana Press Inc.",
pages = "361--367",
booktitle = "Current Clinical Neurology",
}