Abstract
This study examined the impact of motivational contingencies (reinforcement and punishment) on go/no-go (GNG) task performance in girls and boys with ADHD relative to typically developing (TD) children and associations with prefrontal anatomy. Children ages 8-12 with ADHD (n= 107, 36 girls) and TD controls (n= 95, 34 girls) completed a standard and a motivational GNG task and associations with prefrontal cortex (PFC) surface area were examined. Intrasubject variability (ISV) was lower during the motivational compared to the standard GNG among TD girls and boys, and boys with ADHD, but not among girls with ADHD. A greater reduction in ISV was associated with greater PFC surface area among children with ADHD. This novel demonstration of improvement in ISV with motivational contingencies for boys, but not girls, with ADHD and associations with PFC anatomy informs our understanding of sex differences and motivational factors contributing to ISV in children with ADHD.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 12-23 |
| Number of pages | 12 |
| Journal | Biological Psychology |
| Volume | 110 |
| DOIs | |
| State | Published - Sep 1 2015 |
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Keywords
- ADHD
- Cognition
- Intrasubject variability
- Motivation
- Prefrontal cortex
- Response control
- Sex differences
ASJC Scopus subject areas
- Neuroscience(all)
- Neuropsychology and Physiological Psychology
Cite this
Reduced intrasubject variability with reinforcement in boys, but not girls, with ADHD : Associations with prefrontal anatomy. / Rosch, Keri S.; Dirlikov, Benjamin; Mostofsky, Stewart H.
In: Biological Psychology, Vol. 110, 01.09.2015, p. 12-23.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reduced intrasubject variability with reinforcement in boys, but not girls, with ADHD
T2 - Associations with prefrontal anatomy
AU - Rosch, Keri S.
AU - Dirlikov, Benjamin
AU - Mostofsky, Stewart H
PY - 2015/9/1
Y1 - 2015/9/1
N2 - This study examined the impact of motivational contingencies (reinforcement and punishment) on go/no-go (GNG) task performance in girls and boys with ADHD relative to typically developing (TD) children and associations with prefrontal anatomy. Children ages 8-12 with ADHD (n= 107, 36 girls) and TD controls (n= 95, 34 girls) completed a standard and a motivational GNG task and associations with prefrontal cortex (PFC) surface area were examined. Intrasubject variability (ISV) was lower during the motivational compared to the standard GNG among TD girls and boys, and boys with ADHD, but not among girls with ADHD. A greater reduction in ISV was associated with greater PFC surface area among children with ADHD. This novel demonstration of improvement in ISV with motivational contingencies for boys, but not girls, with ADHD and associations with PFC anatomy informs our understanding of sex differences and motivational factors contributing to ISV in children with ADHD.
AB - This study examined the impact of motivational contingencies (reinforcement and punishment) on go/no-go (GNG) task performance in girls and boys with ADHD relative to typically developing (TD) children and associations with prefrontal anatomy. Children ages 8-12 with ADHD (n= 107, 36 girls) and TD controls (n= 95, 34 girls) completed a standard and a motivational GNG task and associations with prefrontal cortex (PFC) surface area were examined. Intrasubject variability (ISV) was lower during the motivational compared to the standard GNG among TD girls and boys, and boys with ADHD, but not among girls with ADHD. A greater reduction in ISV was associated with greater PFC surface area among children with ADHD. This novel demonstration of improvement in ISV with motivational contingencies for boys, but not girls, with ADHD and associations with PFC anatomy informs our understanding of sex differences and motivational factors contributing to ISV in children with ADHD.
KW - ADHD
KW - Cognition
KW - Intrasubject variability
KW - Motivation
KW - Prefrontal cortex
KW - Response control
KW - Sex differences
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UR - http://www.scopus.com/inward/citedby.url?scp=84937116107&partnerID=8YFLogxK
U2 - 10.1016/j.biopsycho.2015.06.010
DO - 10.1016/j.biopsycho.2015.06.010
M3 - Article
C2 - 26141238
AN - SCOPUS:84937116107
VL - 110
SP - 12
EP - 23
JO - Biological Psychology
JF - Biological Psychology
SN - 0019-493X
ER -