TY - JOUR
T1 - Red blood cell storage
T2 - How long is too long?
AU - Koch, Colleen G.
AU - Figueroa, Priscilla I.
AU - Li, Liang
AU - Sabik, Joseph F.
AU - Mihaljevic, Tomislav
AU - Blackstone, Eugene H.
PY - 2013/11
Y1 - 2013/11
N2 - Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the "storage lesion." Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.
AB - Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the "storage lesion." Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.
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U2 - 10.1016/j.athoracsur.2013.05.116
DO - 10.1016/j.athoracsur.2013.05.116
M3 - Review article
C2 - 24090578
AN - SCOPUS:84887108554
SN - 0003-4975
VL - 96
SP - 1894
EP - 1899
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 5
ER -