Red blood cell storage: How long is too long?

Colleen G. Koch, Priscilla I. Figueroa, Liang Li, Joseph F. Sabik, Tomislav Mihaljevic, Eugene H. Blackstone

Research output: Contribution to journalReview articlepeer-review

51 Scopus citations


Red blood cells (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the "storage lesion." Evidence suggests that the longer the RBC product is stored, the less effective is the transfused blood. Many studies linking morbidity to transfusion have not considered duration of RBC storage as a variable that may modulate the effect. In addition, the effects of supply and demand and RBC inventory management strategies have been incompletely investigated. It is possible to envision a blood management system based on modern inventory management strategies that could greatly reduce storage duration.

Original languageEnglish (US)
Pages (from-to)1894-1899
Number of pages6
JournalAnnals of Thoracic Surgery
Issue number5
StatePublished - Nov 2013
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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