Recurrent Pseudomembranous Colitis Unassociated with Prior Antibiotic Therapy

Morry Moskovitz, John G. Bartlett

Research output: Contribution to journalArticle


Fulminant and recurring pseudomembranous colitis developed in an elderly woman without prior antibiotic administration within the previous year. Stool culture yielded Clostridium difficile, and tissue cultures showed C difficile cytotoxin. Treatment with vancomycin hydrochloride was initially successful, but a serious relapse after its discontinuation necessitated low-dose long-term prophylaxis. Clostridium difficile may be responsible for pseudomembranous colitis unassociated with antibiotic therapy.

Original languageEnglish (US)
Pages (from-to)663-664
Number of pages2
JournalArchives of internal medicine
Issue number5
StatePublished - Apr 1981
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine

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