Recurrent Pseudomembranous Colitis Unassociated with Prior Antibiotic Therapy

Morry Moskovitz, John G. Bartlett

Research output: Contribution to journalArticle

Abstract

Fulminant and recurring pseudomembranous colitis developed in an elderly woman without prior antibiotic administration within the previous year. Stool culture yielded Clostridium difficile, and tissue cultures showed C difficile cytotoxin. Treatment with vancomycin hydrochloride was initially successful, but a serious relapse after its discontinuation necessitated low-dose long-term prophylaxis. Clostridium difficile may be responsible for pseudomembranous colitis unassociated with antibiotic therapy.

Original languageEnglish (US)
Pages (from-to)663-664
Number of pages2
JournalArchives of internal medicine
Volume141
Issue number5
DOIs
StatePublished - Apr 1981
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine

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