Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis

Robert W. Foley; Nathan T. Tagg; Matthew K. Schindler; Kaylan M. Fenton; Daniel S. Reich; Irene Cortese; Ellen M. Mowry

doi:10.1177/1352458517702533

Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis

Robert W. Foley, Nathan T. Tagg, Matthew K. Schindler, Kaylan M. Fenton, Daniel S. Reich, Irene Cortese, Ellen M. Mowry

School of Medicine

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.

Original language	English (US)
Pages (from-to)	1424-1427
Number of pages	4
Journal	Multiple Sclerosis
Volume	23
Issue number	10
DOIs	https://doi.org/10.1177/1352458517702533
State	Published - Sep 1 2017

Keywords

MRI
Multiple sclerosis
disease-modifying therapies
natalizumab

ASJC Scopus subject areas

Neurology
Clinical Neurology

Access to Document

10.1177/1352458517702533

Cite this

@article{dbdcc3119077494c996941f294581b3d,

title = "Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis",

abstract = "Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.",

keywords = "MRI, Multiple sclerosis, disease-modifying therapies, natalizumab",

author = "Foley, {Robert W.} and Tagg, {Nathan T.} and Schindler, {Matthew K.} and Fenton, {Kaylan M.} and Reich, {Daniel S.} and Irene Cortese and Mowry, {Ellen M.}",

note = "Publisher Copyright: {\textcopyright} 2017, {\textcopyright} The Author(s), 2017.",

year = "2017",

month = sep,

day = "1",

doi = "10.1177/1352458517702533",

language = "English (US)",

volume = "23",

pages = "1424--1427",

journal = "Multiple Sclerosis",

issn = "1352-4585",

publisher = "SAGE Publications Ltd",

number = "10",

}

TY - JOUR

T1 - Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis

AU - Foley, Robert W.

AU - Tagg, Nathan T.

AU - Schindler, Matthew K.

AU - Fenton, Kaylan M.

AU - Reich, Daniel S.

AU - Cortese, Irene

AU - Mowry, Ellen M.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.

AB - Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.

KW - MRI

KW - Multiple sclerosis

KW - disease-modifying therapies

KW - natalizumab

UR - http://www.scopus.com/inward/record.url?scp=85043348777&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043348777&partnerID=8YFLogxK

U2 - 10.1177/1352458517702533

DO - 10.1177/1352458517702533

M3 - Article

C2 - 28639536

AN - SCOPUS:85043348777

SN - 1352-4585

VL - 23

SP - 1424

EP - 1427

JO - Multiple Sclerosis

JF - Multiple Sclerosis

IS - 10

ER -

Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this