Recurrent natalizumab-related aseptic meningitis in a patient with multiple sclerosis

Robert W. Foley, Nathan T. Tagg, Matthew K. Schindler, Kaylan M. Fenton, Daniel S. Reich, Irene Cortese, Ellen M. Mowry

Research output: Contribution to journalArticlepeer-review

Abstract

Natalizumab is a recombinant humanized monoclonal antibody that decreases T-cell migration into the central nervous system (CNS) through α4 integrin:adhesion-molecule inhibition, thereby increasing the risk for opportunistic CNS infection. Herein, we report a case of infusion-associated aseptic meningitis in a patient receiving natalizumab.

Original languageEnglish (US)
Pages (from-to)1424-1427
Number of pages4
JournalMultiple Sclerosis
Volume23
Issue number10
DOIs
StatePublished - Sep 1 2017

Keywords

  • MRI
  • Multiple sclerosis
  • disease-modifying therapies
  • natalizumab

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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