Recurrences in tuberculosis in a cohort of human immunodeficiency virus-infected patients: The influence of highly active antiretroviral therapy

Juan Pablo Millet, Angels Orcau, Martí Casals, Patricia Garcia De Olalla, Joan A. Caylà

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Little is known about recurrent tuberculosis (TB) among HIV-infected patients and the influence of highly active antiretroviral therapy (HAART). Methods: A population-based retrospective longitudinal study was conducted on all HIV-infected TB patients in Barcelona (Spain) notified in 1987-2003, and followed up until 2005. TB recurrence and HAART influence were analysed according to calendar period. Results: Patients with no-treatment and those in pre-HAART had more risk of TB recurrence (RR: 2.3; CI: 1-5.8 and RR: 4.8; CI: 2-12). Conclusions: HAART decreases probability of TB recurrence and should be extended to all cases.

Original languageEnglish (US)
Pages (from-to)227-229
Number of pages3
JournalEnfermedades Infecciosas y Microbiologia Clinica
Volume31
Issue number4
DOIs
StatePublished - Apr 2013

Keywords

  • Highly active antiretroviral therapy
  • Human immunodeficiency virus
  • Recurrence
  • Relapse
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)

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