Rectal mass caused by Treponema pallidum: Confirmation by immunofluorescent staining

Thomas C. Quinn, Sheila A. Lukehart, Steven Goodell, Emmanuel Mkrtichian, Michael D. Schuffler, King K. Holmes

Research output: Contribution to journalArticle

Abstract

A 37-yr-old homosexual man presented with mild anorectal symptoms, a diffuse maculopapular rash, constitutional symptoms, and a reactive serologic test for syphilis. Sigmoidoscopy revealed a 2 × 2-cm indurated rectal mass 5 cm above the anal verge. Darkfield examination of rectal exudate revealed motile treponemes and rectal biopsy of the mass showed diffuse infiltration of plasma cells and lymphocytes. Large numbers of spirochetes were present on silver stain of the rectal biopsy specimen and these were shown to be Treponema pallidum by indirect immunofluorescence. The rectal mass and symptoms resolved following penicillin therapy. This case and a review of previously reported cases of anorectal syphilis emphasize the significance of these often neglected and misdiagnosed lesions of syphilis.

Original languageEnglish (US)
Pages (from-to)135-139
Number of pages5
JournalGastroenterology
Volume82
Issue number1
DOIs
StatePublished - Jan 1982

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Fingerprint Dive into the research topics of 'Rectal mass caused by Treponema pallidum: Confirmation by immunofluorescent staining'. Together they form a unique fingerprint.

  • Cite this

    Quinn, T. C., Lukehart, S. A., Goodell, S., Mkrtichian, E., Schuffler, M. D., & Holmes, K. K. (1982). Rectal mass caused by Treponema pallidum: Confirmation by immunofluorescent staining. Gastroenterology, 82(1), 135-139. https://doi.org/10.1016/0016-5085(82)90136-6