Rectal cancer clinical practice guidelines in oncology

Paul F. Engstrom, Al B. Benson, Yi Jen Chen, Michael A. Choti, Raza A. Dilawari, Charles A. Enke, Marwan G. Fakih, Charles Fuchs, Krystyna Kiel, James A. Knol, Lucille A. Leong, Kirk A. Ludwig, Edward W. Martin, Sujata Rao, M. Wasif Saif, Leonard Saltz, John M. Skibber, Alan P. Venook, Timothy J. Yeatman

Research output: Contribution to journalArticle

Abstract

The NCCN Rectal Cancer Guidelines panel believes that a multidisciplinary approach is necessary for treating patients with colorectal cancer. Patients with T1 or T2 lesions that are node-negative by endorectal ultrasound and who meet carefully defined criteria can be treated with a transanal excision. Abdominal peritoneal resection or low anterior resection with total mesorectal excision is appropriate for all other rectal lesions. Either preoperative chemoradiation or postoperative chemoradiotherapy is standard for patients with suspected or proven serosal invasion (pT3) or regional node involvement. Patients with recurrent localized disease should be considered for resection with or without radiotherapy. Chemotherapy regimens using irinotecan or oxaliplatin should be considered for patients with distant metastasis. The panel endorses the concept that treating patients in a clinical trial has priority over standard or accepted therapy.

Original languageEnglish (US)
Pages (from-to)492-508
Number of pages17
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume3
Issue number4
StatePublished - Jul 2005

Fingerprint

Rectal Neoplasms
Practice Guidelines
oxaliplatin
irinotecan
Chemoradiotherapy
Colorectal Neoplasms
Radiotherapy
Clinical Trials
Guidelines
Neoplasm Metastasis
Drug Therapy

Keywords

  • Adjuvant chemotherapy
  • Adjuvant radiotherapy
  • Colorectal surgery
  • Fluorouracil
  • Irinotecan
  • NCCN clinical practice guidelines
  • Neoplasm recurrence
  • Neoplasm staging
  • Oxaliplatin
  • Rectal neoplasms

ASJC Scopus subject areas

  • Oncology

Cite this

Engstrom, P. F., Benson, A. B., Chen, Y. J., Choti, M. A., Dilawari, R. A., Enke, C. A., ... Yeatman, T. J. (2005). Rectal cancer clinical practice guidelines in oncology. JNCCN Journal of the National Comprehensive Cancer Network, 3(4), 492-508.

Rectal cancer clinical practice guidelines in oncology. / Engstrom, Paul F.; Benson, Al B.; Chen, Yi Jen; Choti, Michael A.; Dilawari, Raza A.; Enke, Charles A.; Fakih, Marwan G.; Fuchs, Charles; Kiel, Krystyna; Knol, James A.; Leong, Lucille A.; Ludwig, Kirk A.; Martin, Edward W.; Rao, Sujata; Saif, M. Wasif; Saltz, Leonard; Skibber, John M.; Venook, Alan P.; Yeatman, Timothy J.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 3, No. 4, 07.2005, p. 492-508.

Research output: Contribution to journalArticle

Engstrom, PF, Benson, AB, Chen, YJ, Choti, MA, Dilawari, RA, Enke, CA, Fakih, MG, Fuchs, C, Kiel, K, Knol, JA, Leong, LA, Ludwig, KA, Martin, EW, Rao, S, Saif, MW, Saltz, L, Skibber, JM, Venook, AP & Yeatman, TJ 2005, 'Rectal cancer clinical practice guidelines in oncology', JNCCN Journal of the National Comprehensive Cancer Network, vol. 3, no. 4, pp. 492-508.
Engstrom PF, Benson AB, Chen YJ, Choti MA, Dilawari RA, Enke CA et al. Rectal cancer clinical practice guidelines in oncology. JNCCN Journal of the National Comprehensive Cancer Network. 2005 Jul;3(4):492-508.
Engstrom, Paul F. ; Benson, Al B. ; Chen, Yi Jen ; Choti, Michael A. ; Dilawari, Raza A. ; Enke, Charles A. ; Fakih, Marwan G. ; Fuchs, Charles ; Kiel, Krystyna ; Knol, James A. ; Leong, Lucille A. ; Ludwig, Kirk A. ; Martin, Edward W. ; Rao, Sujata ; Saif, M. Wasif ; Saltz, Leonard ; Skibber, John M. ; Venook, Alan P. ; Yeatman, Timothy J. / Rectal cancer clinical practice guidelines in oncology. In: JNCCN Journal of the National Comprehensive Cancer Network. 2005 ; Vol. 3, No. 4. pp. 492-508.
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