Recruitment of proteins to modulate protein-protein interactions

Research output: Contribution to journalShort survey

Abstract

The use of a 'borrowed' protein surface to either enhance or inhibit the interaction of a small ligand with its protein target has been reported recently. This approach represents a general method for modulating protein-protein interactions and may find many applications in both biology and medicine.

Original languageEnglish (US)
Pages (from-to)R213-R215
JournalChemistry and Biology
Volume6
Issue number8
DOIs
StatePublished - Aug 1999
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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