Recruitment and retention strategies in a clinical trial for children with chronic hepatitis c infection

Aparna Roy, Whitney Lieb, Beth Garrett, Marcia Hodik, Ann Klipsch, Melissa Young, Bruce Barton, Kathleen B. Schwarz

Research output: Contribution to journalArticlepeer-review

Abstract

Successful strategies for recruitment and retention (R & R) in pediatric trials are needed. The purpose of our study was to analyze the effectiveness of R&R in a trial for children with hepatitis C. Recruitment strategies were (1) Initial (months 0-12) and (2) extra effort (months 13-18). Initial strategies enrolled 70/114 (61%) of patients. Extra effort strategies included: (1) radio broadcasts, (2) contact with adult hepatologists, (3) dissemination of study material and (4) modification of the exclusion criteria. The overall retention rate was 84% at 2. years. Lessons learned will be valuable in designing future pediatric trials.

Original languageEnglish (US)
Pages (from-to)243-248
Number of pages6
JournalJournal of pediatric nursing
Volume28
Issue number3
DOIs
StatePublished - May 2013

Keywords

  • Hepatitis C virus
  • Pediatric clinical trials
  • Recruitment
  • Retention

ASJC Scopus subject areas

  • Pediatrics

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